COMPARISON OF THE LIVER FATTY ACIDS CONTENT IN RATS FED CANOLA AND PALM OIL REACH DIET
Abstract
Due to its low costs and physical and chemical properties the palm oil is the major oil produced and used in food industry. We compare the influence of olive and palm oils on the plasma lipid profile and the liver fatty acids content of experimental animals (rats). Male and female rats were divided into the control Canola oil (CO) group and the Palm oil (PO) group where the control group had 30 % of fat from a daily calorie intake whereas the CO and PO groups substitute 5 % of fat of canola and palm oils. Additionally, one female group had 10 % of palm oil substitution of dietary fat (PO2 group). Consumption of these diets causes a significant increase in plasma triglycerides in all experimental groups compared to the control group, a total cholesterol increase in the PO2 group. The liver fatty acids profile dose-dependently reflects the diet content. Palm oil decreases the trans-fatty acids amount compared to the control and CO groups but also decreases the level of essential a-linolenic acid which is considered as the negative effect of palm oil.
About the Authors
S. N. Kirko
Institute of Biochemistry of Biologically Active Compounds of the National Academy of Sciences of Belarus
Belarus
Researcher
Belarus
Researcher
V. A. Gurinovich
Institute of Biochemistry of Biologically Active Compounds of the National Academy of Sciences of Belarus
Belarus
Ph. D. (Biol.), Leading researcher.
Belarus
Ph. D. (Biol.), Leading researcher.
E. P. Lukienko
Institute of Biochemistry of Biologically Active Compounds of the National Academy of Sciences of Belarus
Belarus
Ph. D. (Med.), Senior researcher.
Belarus
Ph. D. (Med.), Senior researcher.
A. G. Moiseenok
Institute of Biochemistry of Biologically Active Compounds of the National Academy of Sciences of Belarus
Belarus
Corresponding Member, D. Sc. (Biol.), Professor, Head of the Division.
Belarus
Corresponding Member, D. Sc. (Biol.), Professor, Head of the Division.
V. U. Buko
Institute of Biochemistry of Biologically Active Compounds of the National Academy of Sciences of Belarus
Belarus
D. Sc. (Biol.), Professor, Head of the Department.
Belarus
D. Sc. (Biol.), Professor, Head of the Department.
References
1. May, C. Y. Research advancements in palm oil nutrition / C. Y. May, K. Nasaretman // Eur. J. Lip. Sci. Technol. – 2014. – Vol. 116, N 10. – P. 1301–1315.
2. Choudhury, N. Comparison of palmolein and olive oil: effects on plasma lipids and vitamin E in young adults /N. Choudhury, L. Tan, A. S. Truswell // Am. J. Clin. Nutr. – 1995. – Vol. 61, N 5. – P. 1043–1051.
3. Mozaffarian, D. Health effects of trans-fatty acids: experimental and observational evidence / D. Mozaffarian, A. Aro, W. C. Willett // Eur. J. Clin. Nutr. – 2009. – Vol. 63, suppl. 2. – P. S5–S21.
4. Effects of partially hydrogenated, semi-saturated, and high oleate vegetable oils on inflammatory markers and lipids / K. T. Teng [et al.] // Lipids. – 2010. – Vol. 45, N 5. – P. 385–392.
5. “Rape oil in value close to olive oil!”, Komsomol’skaya pravda v Belarusi [Komsomolskaya Pravda in Belarus], 2012, Available at: http://www.kp.by/daily/25875/2839228/, (Accessed 27 April 2012).
6. Mozaffarian, D. Quantitative effects on cardiovascular risk factors and coronary heart disease risk of replacing partially hydrogenated vegetable oils with other fats and oils / D. Mozaffarian, R. Clarke // Eur. J. Clin. Nutr. – 2009. – Vol. 63, suppl. 2. – P. S22–S33.
7. Palm and partially hydrogenated soybean oils adversely alter lipoprotein profiles compared with soybean and canola oils in moderately hyperlipidemic subjects / V. López [et al.] // Am. J. Clin. Nut. – 2006. – Vol. 84, N 1. – P. 54–62.
8. Folch, J. A simple method for the isolation and purification of total lipides from animal tissues / J. Folch, M. Lees,
9. G. H. Sloane // J. Biol. Chem. – 1957. – Vol. 226, N 1. – P. 497–509.
10. Evershed, R. P. Lipid analyses. A practical approach / R. P. Evershed. – Oxford, 1992. – 22 p.
11. Hitchcock, C. Developments in food analyses / C. Hitchcock, E. W. Hammond. – London, 1980. – 128 p.
12. Mensink, R. P. Effect of dietary trans fatty acids on high-density and low-density lipoprotein cholesterol levels in healthy subjects / R. P. Mensink, M. B. Katan // New Eng. J. Med. – 1990. – Vol. 323. – P. 439–444.
13. Effect of dietary cis and trans fatty acids on serum lipoprotein[a] levels in humans / R. P. Mensink [et al.] // J. Lip. Res. – 1992. – Vol. 33. – P. 1493–1501.
14. Dietary trans fatty acid: effects on plasma lipids and lipoproteins of healthy men and women / J. T. Judd [et al.] // Am. J. Clin. Nutr. – 1994. – Vol. 59. – P. 861–868.
15. Dietary fat and risk of coronary heart disease in men: сohort followup study in the United States / A. Ascherio [et al.] // B. M. J. – 1996. – Vol. 313. – P. 84–90.
16. Dietary fat intake and the risk of coronary heart disease in women / F. B. Hu [et al.] // N. Engl. J. Med. – 1997. – Vol. 337. – P. 1491–1499.
17. Intake of fatty acids and risk of coronary heart disease in a cohort of Finnish men. The alphatocopherol, betacarotene cancer prevention study / P. Pietinen [et al.] // Am. J. Epidemiol. – 1997. – Vol. 145. – P. 876–887.
18. Association between trans fatty acid intake and 10year risk of coronary heart disease in the Zutphen Elderly Study: a prospective populationbased study / C. M. Oomen [et al.] // Lancet. – 2001. – Vol. 357. – P. 746–751.
19. Dietary fat intake and risk of coronary heart disease in women: 20 years of followup of the Nurse’s Health Study /K. Oh [et al.] // Am. J. Epidemiol. – 2005. – Vol. 161. – P. 672–679.
20. Plasma phospholipid trans-fatty acids levels, cardiovascular diseases, and total mortality: the cardiovascular health study / O. Wang [et al.] // J. Am. Heart. Assoc. – 2014. – Vol. 3. – P. e000914.
21. Micha, R. Trans fatty acids: effects on metabolic syndrome, heart disease and diabetes / R. Micha, D. Mozaffarian // Nat. Rev. Endocrinol. – 2009. – Vol. 5. – P. 335–344.
22. Medvedev O. S., Medvedeva N. A. “Modern concepts of a possible influence of palm oil on the human health”, Voprosy pitaniya [Nutritional issues], 2016, vol. 85, no. 1, pp. 5–18.
Review
For citations:
Kirko S.N., Gurinovich V.A., Lukienko E.P., Moiseenok A.G., Buko V.U. COMPARISON OF THE LIVER FATTY ACIDS CONTENT IN RATS FED CANOLA AND PALM OIL REACH DIET. Proceedings of the National Academy of Sciences of Belarus, Medical series. 2017;(1):29-37. (In Russ.)
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