vestimИзвестия Национальной академии наук Беларуси. Серия медицинских наукProceedings of the National Academy of Sciences of Belarus, Medical series1814-60232524-2350The Republican Unitary Enterprise Publishing House "Belaruskaya Navuka"vestim-346Research ArticleКЛИНИЧЕСКАЯ И ЭКСПЕРИМЕНТАЛЬНАЯ МЕДИЦИНАCLINICAL AND EXPERIMENTAL MEDICINEСРАВНИТЕЛЬНАЯ ОЦЕНКА ЖИРНОКИСЛОТНОГО СОСТАВА ПЕЧЕНИ КРЫС ПРИ ВКЛЮЧЕНИИ В РАЦИОН РАПСОВОГО И ПАЛЬМОВОГО МАСЕЛCOMPARISON OF THE LIVER FATTY ACIDS CONTENT IN RATS FED CANOLA AND PALM OIL REACH DIETКиркоС. Н.KirkoS. N.

науч. сотрудник.

Researcher

skirko2002@yahoo.comГуриновичВ. А.GurinovichV. A.

канд. биол. наук, вед. науч. сотрудник.

Ph. D. (Biol.), Leading researcher.

val@bioch.basnet.byЛукиенкоЕ. П.LukienkoE. P.

канд. мед. наук, ст. науч. сотрудник

Ph. D. (Med.), Senior researcher.

val@bioch.basnet.byМойсеёнокА. Г.MoiseenokA. G.

чл.-кор., д-р биол. наук, профессор, заведующий отделом.

Corresponding Member, D. Sc. (Biol.), Professor, Head of the Division.

andrey.moiseenok@tut.byБукоВ. У.BukoV. U.

д-р биол. наук, профессор, заведующий отделом.

D. Sc. (Biol.), Professor, Head of the Department.

vu.buko@tut.byИнститут биохимии биологически активных соединений НАН БеларусиInstitute of Biochemistry of Biologically Active Compounds of the National Academy of Sciences of Belarus201701032017012937Copyright © Кирко С.Н., Гуринович В.А., Лукиенко Е.П., Мойсеёнок А.Г., Буко В.У., 20172017Кирко С.Н., Гуринович В.А., Лукиенко Е.П., Мойсеёнок А.Г., Буко В.У.Kirko S.N., Gurinovich V.A., Lukienko E.P., Moiseenok A.G., Buko V.U.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://vestimed.belnauka.by/jour/article/view/346

Состав и физико-химические свойства пальмового масла обусловливают его широкое применение в пищевой промышленности при производстве продуктов питания и в качестве замены гидрогенизированных ненасыщенных жиров растительного происхождения. Целью настоящей работы было оценить, как присутствие пальмового и рапсового масел в диете влияет на абсорбцию и накопление в печени основных насыщенных и ненасыщенных жирных кислот (ЖК), а также на уровень транс-ЖК. Экспериментальные животные (крысы, отдельно самцы и самки) были разделены на контрольную группу и группы крыс, получавших рапсовое и пальмовое масла в объеме 5  % от общего жирового содержимого диеты (30  % от суточного рациона). Самки еще одной группы получали увеличенную дозу пальмового масла (10  % от жирового рациона). Сравнительная оценка уровня холестерина в плазме крови показала достоверное его увеличение в группе крыс, у которых отмечалось большое содержание пальмового масла. Уровень триглицеридов был достоверно повышену животных всех опытных групп. Спектр жирных кислот в печени дозозависимо отражал жирнокислотный состав диеты. При потреблении пальмового масла уменьшалось содержание транс-ЖК по сравнению с таковым в группе контроляи в группе животных, в рационе которых было рапсовое масло. В то же время снижение уровня незаменимой а-линоленовой кислоты являлось негативным  эффектом пальмового масла.

Due to its low costs and physical and chemical properties the palm oil is the major oil produced and used in food industry. We compare the influence of olive and palm oils on the plasma lipid profile and the liver fatty acids content of experimental animals (rats). Male and female rats were divided into the control Canola oil (CO) group and the Palm oil (PO) group where the control group had 30  % of fat from a daily calorie intake whereas the CO and PO groups substitute 5  % of fat of canola and palm oils. Additionally, one female group had 10  % of palm oil substitution of dietary fat (PO2 group). Consumption of these diets causes a significant increase in plasma triglycerides in all experimental groups compared to the control group, a total cholesterol increase in the PO2 group. The liver fatty acids profile dose-dependently reflects the diet content. Palm oil decreases the trans-fatty acids amount compared to the control and CO groups but also decreases the level of essential a-linolenic acid which is considered as the negative effect of palm oil.

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The authors declare that there are no conflicts of interest present.