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Predictors of adverse events in patients with different emotional status at postinfarction cardiosclerosis

Abstract

This article is devoted to the study of the frequency and risk factors for adverse outcomes among patients with postinfarction cardiosclerosis. The study included 400 patients with a history of first myocardial infarction. The study found that within a year, recurrent myocardial infarction occurred in 92 (23 %) patients died of 26 (6.5 %) patients. The group of patients with recurrent myocardial infarction has a large number of people with depressive disorders that are associated with low levels of trait anxiety, anterior localization of myocardial infarction, a significant decrease in the contractile function of the left ventricle and the enlargement of the left ventricular myocardium, more frequent development of tachyarrhythmias, as well as an increase in the concentration of pro-inflammatory cytokines. For the group of patients with lethal characteristic family history of early coronary artery disease, the prevalence of individuals with situational anxiety, more frequent development of tachyarrhythmias, reduced the contractility of the myocardium and the left ventricular remodeling, higher values of total cholesterol and low-density lipoprotein, as well as the concentration of NT-fragment brain natriuretic peptide.

About the Authors

A. F. Pinchuk
Belarusian State Medical University
Belarus


N. P. Mitkovskaya
Belarusian State Medical University
Belarus


T. V. Statkevich
Belarusian State Medical University
Belarus


L. V. Kartun
Belarusian State Medical University
Belarus


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Review

For citations:


Pinchuk A.F., Mitkovskaya N.P., Statkevich T.V., Kartun L.V. Predictors of adverse events in patients with different emotional status at postinfarction cardiosclerosis. Proceedings of the National Academy of Sciences of Belarus, Medical series. 2015;(4):92-96. (In Russ.)

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ISSN 1814-6023 (Print)
ISSN 2524-2350 (Online)