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Peroxidation state of plasma proteins inrats with diabetes mellitus and arterial hypertension

Abstract

The peroxidation state of plasma proteins in rats with diabetes mellitus and arterial hypertension was studied. Data showed that the process of peroxidation of plasma proteins in experimental animals is multidirectional in the studied pathological state. It increases at diabetes mellitus and goes down at arterial hypertension. Thus, the nature of peroxidation of plasma proteins can be one of the early indicators of tissue damage, which justifies a further investigation of the role of free radical modification of proteins in the biochemical mechanisms of the formation and progression of various pathological states such as diabetes mellitus and arterial hypertension, as well as the use of this mechanism in the diagnosis of different organism states.

About the Authors

Е. Калиновская
Институт физиологии НАН Беларуси
Belarus


С. Кондрашова
Институт физиологии НАН Беларуси
Belarus


Е. Благун
Институт физиологии НАН Беларуси
Belarus


Л. Павловец
Институт физиологии НАН Беларуси
Belarus


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, , , Peroxidation state of plasma proteins inrats with diabetes mellitus and arterial hypertension. Proceedings of the National Academy of Sciences of Belarus, Medical series. 2014;(4):78-81. (In Russ.)

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ISSN 1814-6023 (Print)
ISSN 2524-2350 (Online)