Varicose disease in pregnant women: clinical patterns and duplex ultrasound investigation of the veins
https://doi.org/10.29235/1814-6023-2022-19-3-337-344
Abstract
The objective of the study was to improve the medical care of pregnant women with varicose disease based on the results of duplex ultrasound examination of the veins of the lower extremities, as well as on the clinical and laboratory parameters.
We evaluated the data of 128 pregnant women with varicose veins and performed ultrasound to examine the venous system measuring the diameter of the great saphenous vein (GSV) into saphenofemoral junction, midthigh, lower thigh and investigating the venous reflux.
The diameter of competent and incompetent GSVsincreased between the first and third trimester in the both groups(p < 0.001). The mean diameter was 4.3 (2.69–5.86) mm in the main group at 22–24 weeks of gestation, 4.6 (2.96‒5.86) mm at 32‒34 weeks, 4.5 (2.91–5.74) mm ‒ after delivery. The diameter of the GSV with reflux was significantly larger than that of GSVs without reflux in the saphenofemoral junction (R = 0.758, p < 0.001).
Pregnancy induces the alterations of venous physiology. Examination of clinical and ultrasound data of pregnant women with varicose veins is an important step to prevent the disease progression during pregnancy and childbirth.
About the Authors
L. F. Mozhejko
Belarusian State Medical University
Belarus
Belarus
Liudmila F. Mozhejko – D. Sc. (Med.), Professor, Head of the Department.
83, Dzerzhinski Ave., 220116, Minsk
Ya. V. Tsikhanovich
Belarusian State Medical University
Belarus
Belarus
Yauheniya V. Tsikhanovich – Assistant.
83, Dzerzhinski Ave., 220116, Minsk
References
1. Lee A., Robertson L., Boghossian S. Progression of varicose veins and chronic venous insufficiency in the general population in the Edinburgh Vein Study. Journal of Vascular Surgery: Venous and Lymphatic Disorders, 2015, vol. 3, no. 1, pp. 18‒26. https://doi.org/10.1016/j.jvsv.2014.09.008
2. Stoiko Yu. M., Kirienko A. I., Zatevakhin I. I., Pokrovskii A. V., Karpenko A. A., Zolotukhin I. A. [et al.]. Russian clinical guidelines for the diagnostics and treatment of chronic venous diseases. Flebologiya [Phlebology], 2018, vol. 12, no. 3, pp. 146–240 (in Russian).
3. Zolotukhin I. A., Seliverstov E. I., Shevtsov Y. N., Avakiants I. P., Nikishkov A. S., Tatarintsev A. M., Kirienko A. I. Prevalence and risk factors for chronic venous disease in the general russian population. European Journal of Vascular and Endovascular Surgery, 2017, vol. 54, no. 6, pp. 752–758. https://doi.org/10.1016/j.ejvs.2017.08.033
4. Dzhenina O. V., Bogachev V. Yu., Bodanskaya A. L. Vulvar and perineal varicose veins in pregnant women. Statsionarozameshchayushchie tekhnologii: Ambulatornaya khirurgiya [Hospital-replacing technologies: Ambulatory surgery], 2019, no. 1–2, pp. 14‒18 (in Russian).
5. Fukaya E., Flores A. M., Lindholm D., Gustafsson S., Zanetti D., Ingelsson E., Leeper N.J. Clinical and genetic determinants of varicose veins. Circulation, 2018, vol. 138, no. 25, pp. 2869‒2880. https://doi.org/10.1161/CIRCULATIONAHA.118.035584
6. Serra R., Ssempijja L., Provenzano M., Andreucci M. Genetic biomarkers in chronic venous disease. Biomarkersin Medicine, 2020, vol. 14, no. 2, pp. 75‒80. https://doi.org/10.2217/bmm-2019-0408
7. Hamel-Desnos C. M., De Maeseneer M.,Josnin M., GilletJ.-L., Allaert F.-A. Greatsaphenous vein diametersin phlebological practice in France: a report of the DIAGRAVES Study by the French Society of Phlebology. European Journal of Vascular and Endovascular Surgery, 2019, vol. 58, no. 1, pp. 96‒103. https://doi.org/10.1016/j.ejvs.2018.09.011
8. Kim M. J., Park P. J., Koo B. H., Lee S. G., Byun G. Y., Lee S. R. association between venous reflux and diameter of great saphenous vein in lower thigh. Journal of Vascular Surgery: Venousand Lymphatic Disorders, 2020, vol. 8, no. 1, pp. 100–105. https://doi.org/10.1016/j.jvsv.2019.04.016
9. Mendoza E., Blättler W., Amsler F. Great saphenous vein diameter at the saphenofemoral junction and proximal thigh as parameters of venous disease class. European Journal of Vascular and Endovascular Surgery, 2013, vol. 45, pp. 76‒83. https://doi.org/10.1016/j.ejvs.2012.10.014
10. Yarygina T. A., Bataeva R. S., Gus A. I. Cerebral-placental-uterine ratio as a novel combined parameter of obstetric doppler ultrasonography. Akusherstvo i ginekologiya [Obstetrics and gynecology], 2020, no. 10, pp. 55‒62.
11. Medvedeva M. V. Prenatal sonography. Moscow, Real’noe vremya Publ., 2005. 560 p. (in Russian).
Review
For citations:
Mozhejko L.F., Tsikhanovich Ya.V. Varicose disease in pregnant women: clinical patterns and duplex ultrasound investigation of the veins. Proceedings of the National Academy of Sciences of Belarus, Medical series. 2022;19(3):337-344. (In Russ.) https://doi.org/10.29235/1814-6023-2022-19-3-337-344
Views: 490
Email this article 