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Congenital anomalies of the lumbosacral spine

https://doi.org/10.29235/1814-6023-2020-17-4-401-408

Abstract

The aim of the study is to compare the structure of the lumbosacral transitional vertebra, which were detected by computed tomography (CT) and identified on dried human sacral, and to discuss possible pathogenetic mechanisms of this congenital malformation. The article presents 9 cases of lumbosacral transitional vertebra, including 6 cases of L5 sacralization and 3 cases of S1 lumbarization. The formation of the transitional lumbosacral vertebra is genetically determined. All types of such developmental anomaly can be detected only on CT. L5 sacralization repeats the process of fusion of the sacral vertebra into a single bone. A lack of the costotransverse bars of the first sacral vertebrae fusion results in the S1 lumbarization.

About the Authors

S. L. Kabak
Belarusian State Medical University
Belarus

Sergei L. Kabak – D. Sc. (Med.), Professor, Head of the Department

83, Dzerzhynski Ave., 220116, Minsk



V. V. Zatochnaya
Belarusian State Medical University
Belarus

Valentina V. Zatochnaya – Senior Lecturer

83, Dzerzhynski Ave., 220116, Minsk



N. O. Zhizhko-Mikhasevich
Republican Scientific and Practical Centre for Traumatology and Orthopedics
Belarus

Natalya O. Zhizhko-Mikhasevich – Radiologist

60/4, Kizhevatov Str., 220024, Minsk



References

1. Chaturvedi A., Klionsky N. B., Nadarajah U., Chaturvedi A., Meyers S. P. Malformed vertebrae: a clinical and imaging review. Insights into Imaging, 2018, vol. 9, no. 3, pp. 343–355. https://doi.org/10.1007/s13244-018-0598-1

2. Esses S. E., Botsford D. J. Surgical anatomy and operative approaches to the sacrum. The adult spine: Principles and practice. Philadelphia, 1997, vol. 2, pp. 2329–2341.

3. Cheng J. S., Song J. K. Anatomy of the sacrum. Neurosurgical Focus, 2003, vol. 15, no. 2, pp. 1–4. https://doi.org/10.3171/foc.2003.15.2.3

4. Mahato N. K. Transitional female sacrum: dimensions, alterations in dorsal pelvic structure, and potential obstetric implications. Oman Medical Journal, 2018, vol. 33, no. 1, p. 22–28. https://doi.org/10.5001/omj.2018.05

5. Khairnar K. B., Rajale M. B. Sacralization of lumbar vertebra. Indian Journal of Basic and Applied Medical Research, 2013, vol. 6, no. 2, pp. 510–514.

6. Shetty A. S., Jetti R. Sacralization of fifth lumbar vertebra – a case report. Austin Journal of Anatomy, 2017, vol. 4, no. 2, pp. 1066–1067. https://doi.org/10.26420/austinjanat.2017.1066

7. Nikumbh R. D., Wanjari A. N., Nikumbh D. B. Morphological study of sacralisation of fifth lumbar vertebra and its clinical relevance. Indian Journal of Anatomy, 2017, vol. 6, no. 2, pp. 119–124. https://doi.org/10.21088/ija.2320.0022.6217.5

8. Bhasin R., Hamid S., Raina S. Sacralization of lumbar vertebrae-its anatomical, embryological and clinical perspective. Global Journal for Research Analysis, 2018, vol. 7, no. 9, pp. 28–30.

9. Mahato N. K. Complete sacralization of L5 vertebrae: traits, dimensions, and load bearing in the involved sacra. Spine Journal, 2010, vol. 10, no. 7, pp. 610–615. https://doi.org/10.1016/j.spinee.2010.04.012

10. Tague R. G. Sacralization is not associated with elongated cervical costal process and cervical rib. Clinical Anatomy, 2011, vol. 24, no. 2, pp. 209–217. https://doi.org/10.1002/ca.21087

11. Castellvi A. E., Goldstein L. A., Chan D. P. Lumbosacral transitional vertebrae and their relationship with lumbar extradural defects. Spine, 1984, vol. 9, no. 5, pp. 493–495. https://doi.org/10.1097/00007632-198407000-00014

12. Wazir S. Sacralisation of lumbar vertebrae. International Journal of Anatomy and Research, 2014, vol. 2, no. 2, pp. 386–389.

13. Patel J. V., Mehta C. M., Patil N. G., Sehgal S. R. Transverse sacralization of lumbar vertebrae: prevalence according to Castellvi classification. International Journal of Research in Orthopedics, 2016, vol. 3, no. 1, p. 116. https://doi.org/10.18203/issn.2455-4510.intjresorthop20164835

14. Uçar D., Uçar B. Y., Coşar Y., Emrem K., Gümüşsuyu G., Mutlu S., Mutlu B., Çaçan M. A., Mertsoy Y., Gümüş H. Retrospective cohort study of the prevalence of lumbosacral transitional vertebra in a wide and well-represented population. Arthritis, 2013, vol. 2013, pp. 1–5. https://doi.org/10.1155/2013/461425

15. Sharma V. A., Sharma D. K., Shukla C. K. Oesteogenic study of lumbosacral transitional vertebra in central India region. Journal of Anatomical Society of India, 2011, vol. 60, no. 2, pp. 212–217. https://doi.org/10.1016/s0003-2778(11)80030-4

16. Krishnamurthy A., Adibatti M. Study on incidence of sacralisation of fifth lumbar vertebra in South Indian population. Italian Journal of Anatomy and Embryology, 2016, vol. 121, no. 1, pp. 60–65.

17. Mallo M., Wellik D. M., Deschamps J. Hox genes and regional patterning of the vertebrate body plan. Developmental Biology, 2010, vol. 344, no. 1, pp. 7–15. https://doi.org/10.1016/j.ydbio.2010.04.024

18. Wellik D. M., Capecchi M. R. Hox10 and Hox11 genes are required to globally pattern the mammalian skeleton. Science, 2003, vol. 301, no. 5631, pp. 363–367. https://doi.org/10.1126/science.1085672

19. Carapuço M., Nóvoa A., Bobola N., Mallo M. Hox genes specify vertebral types in the presomitic mesoderm. Genes and Development, 2005, vol. 19, no. 18, pp. 2116–2121. https://doi.org/10.1101/gad.338705

20. Salsabili N., Hogg D. A. Development of the human sacroiliac joint. Clinical Anatomy, 1991, vol. 4, no. 2, pp. 99–108. https://doi.org/10.1002/ca.980040204

21. Steele D. G., Bramblett C. A. The anatomy and biology of the human skeleton. Texas A&M University Press, 1988. 304 p.

22. Coalson R. E., Tomasek J. J. Musculoskeletal System. Embryology. New York, 1992, pp. 46–56.

23. Bakkum B. W., Bachop W. E. Development of the spine and spinal cord. Clinical Anatomy of the Spine, Spinal Cord, and Ans. St. Louis, 2014, pp. 541–565.

24. Jain A., Kebaish K. M., Sponseller P. D. Sacral-alar-iliac fixation in pediatric deformity: radiographic outcomes and complications. Spine Deformity, 2016, vol. 4, no. 3, pp. 225–229. https://doi.org/10.1016/j.jspd.2015.11.005

25. Makarova A. V., Seroukh A. G. Anomalies of development of vertebral colums. Studencheskii nauchnyi forum : VII Mezhdunarodnaya studencheskaya elektronnaya nauchnaya konferentsiya, 15 fevralya–31 marta 2015 goda [Student scientific forum: VII International student electronic scientific conference, February 15–March 31, 2015]. Available at: http://www.scienceforum.ru/2015/898/11185 (accessed 04.10.2020) (in Russian).


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For citations:


Kabak S.L., Zatochnaya V.V., Zhizhko-Mikhasevich N.O. Congenital anomalies of the lumbosacral spine. Proceedings of the National Academy of Sciences of Belarus, Medical series. 2020;17(4):401-408. (In Russ.) https://doi.org/10.29235/1814-6023-2020-17-4-401-408

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ISSN 1814-6023 (Print)
ISSN 2524-2350 (Online)