Preview

Proceedings of the National Academy of Sciences of Belarus, Medical series

Advanced search

CORRECTION OF METABOLIC DISORDERS DUE TO AMINO ACID COMPOSITIONS AT INTERMITTENT ALCOHOL INTOXICATION

Abstract

The efficiency of amino acid compositions during the correction of the disorders due to intermittent alcohol intoxication in liver, heart and blood of experimental animals is researched. Intermittent alcohol intoxication is followed by the activation of POL processes in blood and liver and by the depletion of the antioxidant system capacity. Changes in the free amino acid pool at alcohol intoxication are expressed in a reduction of the levels of 9 amino acids and ethanolamine in the liver, and also 5 amino acids and ethanolamine in the myocardium. The amino acid composition Tritarg, in comparison with Tavamin and Neyramin has a more expressed correction effect on the POL activation in the blood and the liver. Administration of Tritarg, unlike Tavamin and Neyramin, leads to an increase in the blood plasma of the level of 10 amino acids, ethanolamine and glutathione. Тritarg in comparison with Tavamin and Neyramin shows the well expressed hepatotrophic effect, normalizing the levels of 9 amino acids and glutathione, and has a more expressed positive influence on metabolic deviations at intermittent alcohol intoxication.

For citations:


Lelevich V.V., Lelevich S.V. CORRECTION OF METABOLIC DISORDERS DUE TO AMINO ACID COMPOSITIONS AT INTERMITTENT ALCOHOL INTOXICATION. Proceedings of the National Academy of Sciences of Belarus, Medical series. 2017;(3):22-28. (In Russ.)

Views: 796


Creative Commons License
This work is licensed under a Creative Commons Attribution 4.0 License.


ISSN 1814-6023 (Print)
ISSN 2524-2350 (Online)