Pathomorphological characteristic of experimental Lewis lung carcinoma at correction by competitors of folic acid
Abstract
When studying the efficiency of impact of folic acid competitors on intertwined Lewis carcinoma in experimental animals, it is established that 3-(couple-aminobenzene-sulfamido)-5-metilizoksazol and 2,4-diamino-5-(3,4,5-metoksibenzyl)-pyrimidine have a certain therapeutic effect. The mechanism of action consists both of the cytotoxic influence on tumor cells and of a decrease in the level of their proliferation. The noticeable damaging effect on surrounding non-neoplastic cells is not registered.
For citations:
Demidchik Yu.E., Vladimirskaya T.E., Sherstiuk G.V., Bychkov V.M., Stankevich S.I. Pathomorphological characteristic of experimental Lewis lung carcinoma at correction by competitors of folic acid. Proceedings of the National Academy of Sciences of Belarus, Medical series. 2015;(2):5-9. (In Russ.)
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