Vitamin D deficiency, characteristics of calcium-phosphorus and bone metabolism in healthy children
- Р Р‡.МессенРТвЂВВВВВВВВжер
- РћРТвЂВВВВВВВВнокласснРСвЂВВВВВВВВРєРСвЂВВВВВВВВ
- LiveJournal
- Telegram
- ВКонтакте
- РЎРєРѕРїРСвЂВВВВВВВВровать ссылку
Full Text:
Abstract
The levels of vitamin D have been studied in 113 healthy children (55 boys and 58 girls) from one of the Minsk districts who were divided into 3 age groups: 5-9, 10-13, and 14-17 years. The average level of vitamin D was 32.6 ± 9.2 ng/ml; without distinction of sex. The vitamin D deficiency was found in 7.1 %, and insufficiency in 31.6 % of children. 70.6 % of girls aged 14-17 years had the deficiency and insufficiency of vitamin D. Identified age-related dynamics of changes in the levels of calcium, phosphorus, magnesium, alkaline phosphatase, parathyroid hormone and markers of bone metabolism: osteocalcin and β-cross-lapse in the blood and excretion of calcium and phosphorus in the urine. The decrease in the mineral bone density of the lumbar spine L1-L4 and the total body was diagnosed in 1 child (0.9 %).
Keywords
витамин Д,
дефицит и недостаточность витамина Д,
обмен фосфора и кальция,
маркеры костного метаболизма,
минеральная плотность костной ткани,
здоровые дети,
vitamin D,
vitamin D deficiency and insufficiency,
phosphorus and calcium metabolism,
markers of bone metabolism,
bone mineral density,
healthy children
About the Authors
S. V. Baiko
Belarusian State Medical University
Belarus
Belarus
A. V. Sukalo
Belarusian State Medical University; Belarusian National Academy of Sciences
Belarus
Belarus
K. A. Vasilenka
Minsk City Center of Osteoporosis
Belarus
Belarus
A. V. Adamenka
Minsk City Center of Osteoporosis
Belarus
Belarus
References
1. Mal'tsev, S. V. Metabolizm vitamina D i puti realizatsii ego osnovnykh funktsii / S. V. Mal'tsev, G. Sh. Mansurova // Prakt. meditsina. - 2014. - T. 85, № 9. - S. 12-18.
2. Shesterikova, V. V. Sovremennyi vzglyad na vitamin D / V. V. Shesterikova, I. E. Ivanova, N. V. Sterzhanova // Lechenie i profilaktika. - 2014. - T. 9, № 1. - S. 57-61.
3. Smirnova, G. E. Rol' vitamina D v razvitii detskogo organizma i korrektsiya ego defitsita / G. E. Smirnova, A. V. Vitebskaya, N. A. Shmakov / Consilium medicum. - 2010. - № 34. - S. 7-12.
4. Holick, M. F. Vitamin D deficiency / M. F. Holick // N. Engl. J. Med. - 2007. - Vol. 357, N 3. - P. 266-281.
5. Evaluation, treatment, and prevention of vitamin D deficiency : an Endocrine Society clinical practice guideline / M. F. Holick [et al.] // J. Clin. Endocrinol. Metab. - 2011. - Vol. 97, N 7. - P. 1911-1930.
6. Practical guidelines for the supplementation of vitamin D and the treatment of deficits in Central Europe -recommended vitamin D intakes in the general population and groups at risk of vitamin D deficiency / P. Pludowski [et al.] // Endokrynologia Polska. - 2013. - Vol. 64, N 4. - P. 319-327.
7. Mansbach, J. M. Serum 25-hydroxyvitamin D levels among US children aged 1 to 11 years: do children need more vitamin D? / J. M. Mansbach, A. A. Ginde, C. A. Camargo // Pediatrics. - 2009. - Vol. 124, N 5. - P. 1404-1410.
8. Prevalence of vitamin D deficiency among healthy adolescents / C. M. Gordon [et al.] // Arch. Pediatr. Adolesc. Med. -2004. - Vol. 158, N 6. - P. 531-537.
9. Lyalikov, S. A. Tsentil'nye kharakteristiki antropometricheskikh i laboratornykh pokazatelei u detei v sovremennyi period : instruktsiya po primeneniyu : utv. M-vom zdravookhraneniya Resp. Belarus' 10.04.09 / S. A. Lyalikov, A. V. Sukalo, O. E. Kuznetsov ; GrGMU, BGMU, UZ «GrOKB». - Grodno, 2009. - 94 s.
10. Shcheplyagina, L. A. Istoki osteoporoza vzroslykh lezhat v detskom vozraste / L. A. Shcheplyagina, I. V. Kruglova, T. Yu. Moiseeva // Lechenie i profilaktika - 2013. - Tom 5, № 1. - S. 5-12.
Review
For citations:
Baiko S.V., Sukalo A.V., Vasilenka K.A., Adamenka A.V. Vitamin D deficiency, characteristics of calcium-phosphorus and bone metabolism in healthy children. Proceedings of the National Academy of Sciences of Belarus, Medical series. 2015;(3):14-18. (In Russ.)
Views:
796
ISSN 1814-6023 (Print)
ISSN 2524-2350 (Online)
ISSN 2524-2350 (Online)
Email this article 