Vitamin D deficiency, characteristics of calcium-phosphorus and bone metabolism in healthy children
Abstract
The levels of vitamin D have been studied in 113 healthy children (55 boys and 58 girls) from one of the Minsk districts who were divided into 3 age groups: 5-9, 10-13, and 14-17 years. The average level of vitamin D was 32.6 ± 9.2 ng/ml; without distinction of sex. The vitamin D deficiency was found in 7.1 %, and insufficiency in 31.6 % of children. 70.6 % of girls aged 14-17 years had the deficiency and insufficiency of vitamin D. Identified age-related dynamics of changes in the levels of calcium, phosphorus, magnesium, alkaline phosphatase, parathyroid hormone and markers of bone metabolism: osteocalcin and β-cross-lapse in the blood and excretion of calcium and phosphorus in the urine. The decrease in the mineral bone density of the lumbar spine L1-L4 and the total body was diagnosed in 1 child (0.9 %).
Keywords
витамин Д,
дефицит и недостаточность витамина Д,
обмен фосфора и кальция,
маркеры костного метаболизма,
минеральная плотность костной ткани,
здоровые дети,
vitamin D,
vitamin D deficiency and insufficiency,
phosphorus and calcium metabolism,
markers of bone metabolism,
bone mineral density,
healthy children
About the Authors
S. V. Baiko
Belarusian State Medical University
Belarus
Belarus
A. V. Sukalo
Belarusian State Medical University; Belarusian National Academy of Sciences
Belarus
Belarus
K. A. Vasilenka
Minsk City Center of Osteoporosis
Belarus
Belarus
A. V. Adamenka
Minsk City Center of Osteoporosis
Belarus
Belarus
References
1. Мальцев, С. В. Метаболизм витамина Д и пути реализации его основных функций / С. В. Мальцев, Г. Ш. Мансурова // Практ. медицина. - 2014. - Т. 85, № 9. - С. 12-18.
2. Шестерикова, В. В. Современный взгляд на витамин Д / В. В. Шестерикова, И. Е. Иванова, Н. В. Стержанова // Лечение и профилактика. - 2014. - Т. 9, № 1. - С. 57-61.
3. Смирнова, Г. Е. Роль витамина Д в развитии детского организма и коррекция его дефицита / Г. Е. Смирнова, А. В. Витебская, Н. А. Шмаков / Consilium medicum. - 2010. - № 34. - С. 7-12.
4. Holick, M. F. Vitamin D deficiency / M. F. Holick // N. Engl. J. Med. - 2007. - Vol. 357, N 3. - P. 266-281.
5. Evaluation, treatment, and prevention of vitamin D deficiency : an Endocrine Society clinical practice guideline / M. F. Holick [et al.] // J. Clin. Endocrinol. Metab. - 2011. - Vol. 97, N 7. - P. 1911-1930.
6. Practical guidelines for the supplementation of vitamin D and the treatment of deficits in Central Europe -recommended vitamin D intakes in the general population and groups at risk of vitamin D deficiency / P. Pludowski [et al.] // Endokrynologia Polska. - 2013. - Vol. 64, N 4. - P. 319-327.
7. Mansbach, J. M. Serum 25-hydroxyvitamin D levels among US children aged 1 to 11 years: do children need more vitamin D? / J. M. Mansbach, A. A. Ginde, C. A. Camargo // Pediatrics. - 2009. - Vol. 124, N 5. - P. 1404-1410.
8. Prevalence of vitamin D deficiency among healthy adolescents / C. M. Gordon [et al.] // Arch. Pediatr. Adolesc. Med. -2004. - Vol. 158, N 6. - P. 531-537.
9. Ляликов, С. А. Центильные характеристики антропометрических и лабораторных показателей у детей в современный период : инструкция по применению : утв. М-вом здравоохранения Респ. Беларусь 10.04.09 / С. А. Ляликов, А. В. Сукало, О. Е. Кузнецов ; ГрГМУ, БГМУ, УЗ «ГрОКБ». - Гродно, 2009. - 94 с.
10. Щеплягина, Л. А. Истоки остеопороза взрослых лежат в детском возрасте / Л. А. Щеплягина, И. В. Круглова, Т. Ю. Моисеева // Лечение и профилактика - 2013. - Том 5, № 1. - С. 5-12.
Review
For citations:
Baiko S.V., Sukalo A.V., Vasilenka K.A., Adamenka A.V. Vitamin D deficiency, characteristics of calcium-phosphorus and bone metabolism in healthy children. Proceedings of the National Academy of Sciences of Belarus, Medical series. 2015;(3):14-18. (In Russ.)
Views:
790
Email this article 