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Human genome and new approaches in regenerative medicine

Abstract

The sequencing of the human genome has become a major event in the development of biomedicine that opened real perspectives for the creation of new biotechnologies to be used in clinical practice and for the preparation of new-generation drugs with their precisely defined impact on the functioning of cells, tissues, and the whole organism. There appeared the favorable conditions for the development of extensive studies of embryonic and induced pluripotent stem cells and different technologies for reprogramming human adult cells and their practical use in regenerative medicine. This promising area of bio-medical research is in rapid progress and is widely supported. Now the problems of safety, morals, and ethics are not yet completely solved, but their awareness allows one to hope for success in overcoming possible obstacles in the future.

About the Author

U. K. Sauchanka
Институт философии НАН Беларуси
Belarus


References

1. Савченко В. К. // Актуальные вопросы антропологии. Минск, 2012. Вып. 7. С. 7-33.

2. Hartl D. L., Jones E. W. Essential Genetics. 2nd ed. Boston, 1999. - 552 p.

3. Корочкин Л. И. // Природа. 2005. № 6. C. 3-11.

4. Scholer H. R. Human biotechnology as Social Challenge. Ashgate Publishing, Ltd. 2007. P. 28.

5. Beckmann J., Scheitza S., Wernet P. et al. // Blood. 2007. Vol. 109, N 12. P. 5494-5501.

6. Ulloa-Montoya F., Verfaillie C. M., Hu W. S. // J. Biosci. Bioeng. 2005. Vol. 100, N 1. P. 12-27.

7. Adewumi O., Aflatoonian B., Ahrlund-Richter L. et al. // Nat. Biotechnol. 2007. Vol. 25, N 7. P. 803-816.

8. Mitalipov S., Wolf D. // Biotechnology. 2009. Vol. 114. P. 185-199.

9. Chambers I., Colby D., Robertson M. et al. // Cell. 2003. Vol. 113, N 5. P. 643-655.

10. Boyer L. A., Lee T. I., Cole M. F. et al. // Cell. 2005 Vol. 122, N 6. P. 947-956.

11. Takahashi K., Yamanaka S. // Cell. 2006. Vol. 126, N 4. P. 663-676.

12. Okita K., Ichisaka T., Yamanaka S. // Nature. 2007. Vol. 448, N 7151. P. 313-317.

13. Gurdon J. B., Wilmut I. // Cold Spring Harb Perspect Biol. 2011. doi: 10.1101/cshperspect.a002659 originally published online. May 9, 2011.

14. Swaminathan Nikhil // Sci. Am. News. 30.11.2007. http://www.sciam.com/article.cfm?id=stem-cells-without-cancer.

15. Zhou H., Wu S., Joo J. Y. et al. // Cell Stem Cell. 2009. Vol. 4. P. 381-384.

16. Kim D., Kim C. H., Moon J. I. et al. // Cell Stem Cell. 2009. Vol. 4, N 6. P. 472-476.

17. Takahashi K., Tanabe K., Ohnuki M. et al. // Cell. 2007. Vol. 131, N 5. P. 861-872.

18. Yu J., Vodyanik M. A., Smuga-Otto K. et al. // Science. 2007. Vol. 318, N 5858. P. 1917-1920.

19. Huangfu D., Maehr R., Guo W. et al. // Nat. Biotechnol. 2008. Vol. 26, N 7. P. 795-797.

20. Desponts S., Desponts C., Do J. T. et al. // Cell Stem Cell. 2008. Vol. 3, N 5. P. 568-574.

21. Zhou Wi, Freed C. R. // Stem Cells. 2009. Vol. 27, N 11. P. 2667-2674.

22. Yamanaka K., Nakagawa M., Hyenjong H. et al. // Science. 2008. Vol. 322, N 5903. Р. 949-953.

23. Judson R. L., Babiarz J. E., Venere M., Blelloch R. // Nat. Biotechnol. 2009. Vol. 27. Р. 459-461.

24. Barrientos S., Stojadinovic O. et al. // Wound Repair Regen. 2008. Vol. 16, N 5. P. 585-601.

25. Tong M., Tuk B. et al. // Wound Repair Regen. Vol. 17, N 6. P. 840-852.

26. Van Neck J. W., Zuidema Y. S. et al. // Eur. J. Dermatol. 2011. Vol. 21, N 3. P. 451-452.

27. Van Neck J., Tuk B., Barritault D., Tong M. Tissue Regeneration - From Basic Biology to Clinical Application. Prof. Jamie Davies (ed.). 2012. P. 69-92.

28. Slack J. M. // J. Pathol. 2009. Vol. 217, N 2. P. 161-168.

29. Wei G., Schubiger G., Harder F., Mtiller A. M. // Stem Cells. 2000. Vol. 18. P. 409-414.

30. Melanie I. W., Setiawan L., Hariharan I. K. // Ann. Rev. of Genetics. 2012. Vol. 46. P. 289-310.

31. Qian L., Huang Y., Spencer C. I., Foley A. et al. // Nature. 2012. (E. pub. 18 April). doi: 10.1038/nature11044.

32. Han D. W., Tapia N., Hermann A. et al. // Cell Stem Cell. 2012. Vol. 10, N 4. P. 465-472.

33. Vierbuchen T., Wernig M. // Nat. Biotechnol. 2011. Vol. 29, N 10. P. 892-907.

34. Liu X., Ory V., Chapman S. et al. // The Am. J. of Pathol. 2012. Vol. 180, N 2. P. 599-607.

35. Terunuma A., Limgala R. P., Park C. J. et al. // Tissue Eng. Part A. 2010. Vol. 16, N 4. P. 1363-1368.

36. Suprynowicz F. A., Upadhyay G., Krawczyk E. et al. // PNAS. 2012. Vol. 109, N 49. P. 20035-20040.

37. Jung D.-W., Williams D. R. // ACS Chem. Biol. 2011. Vol. 6, N 6. P. 553-562.

38. Kim W. H. et al. // ACS Chem. Biol. 2012. Vol. 7, N 4. P. 732-743.

39. Qian L., Huang Y., Spencer C. I. et al. // Nature. 2012. Vol. 485, N 7400. P. 599-604.

40. Jayawardena T. M., Egemnazarov B., Finch E. A. et al. // Circulation Res. 2012. Vol. 110, N 11. P. 1465-1473.

41. Chunhui X. // Trends in Molecular Medicine. 2012. Vol. 18. Iss. 10. P. 575-576.

42. Chen J. X., Krane M., Deutsch M.-A. et al. // Circulation Res. 2012. Vol. 111. P. 50-55.

43. Lian X., Hsiao C., Gisela W. et al. // PNAS. 2012. Vol. 109, N 27. Р. E1848-E1857.

44. Willems E., Cabral-Teixeira J. et al. // Cell Stem Cell. 2012. Vol. 11, N 2. P. 242-252.

45. Yin L., Ohanyan V., Pung Y. F., Chilian W. M. // Circulation Res. 2012. Vol. 110. P. 241-252.

46. Quijada P., Toko H., Fischer K. M. et al. // Circulation Res. 2012. Vol. 111. P. 77-86.

47. Mohsin S., Mohsin K., Toko H. et al. // J. Am. Coll. Cardiol. 2012. Vol. 60, N 14. P. 1278-1287.

48. Zeuner A., Martelli F. et al. // Stem Cells. 2012. Vol. 30. P. 1587-1596.

49. Giarratana M. C., Rouard H., Dumont A. et al. // Blood. 2011. Vol. 118, N 19. P. 5071-5079.

50. Kobari L., Yates F., Oudrhiri N. et al. // Haematologica. 2012. Vol. 97, N 12. P. 1795-1803.

51. Migliaccio A. R., Whitsett C., Papayannopoulou T., Sadelain M. // Cell Stem Cell. 2012. Vol. 10, N 2. P. 115-119.

52. Zhang W., Duan S., Li Y. et al. // Protein Cell. 2012. Vol. 3, N 2. P. 91-97.

53. Lujan E., Chanda S., Ahlenius H. et al. // PNAS. 2012. Vol. 109, N 7. P. 2527-2532.

54. Their M., Worsdorfer P., Lakes Y. B. et al. // Cell Stem Cell. 2012. Vol. 2. Iss. 2. P. 41-44.

55. Han D. W., Tapia N., Hermann A. et al. // Cell Stem Cell. 2012. Vol. 10. Iss. 4. P. 465-472.

56. Sheng C., Zheng Q., Wu J. et al. // Cell Res. 2012. Vol. 22. P. 769-772.

57. Ring K. L., Leslie M., Tong L. et al. // Cell Stem Cell. 2012. Vol. 11. Iss. 1. P. 100-109.

58. Liu G.-H., Yi F., Suzuki K. et al. // Cell Res. 2012. Vol. 22. P. 1087-1091.

59. Peng Y., Huang S., Cheng B. et al. // Ageing Res. Rev. 2013. Vol. 12. P. 103-115. Available online 30 April, 2012. doi. org/10.1016/j.arr.2012.04.005.

60. Bieback K., Kern S., Kocaomer A. et al. // Biomed. Mater. Eng. 2008. Vol. 18. P. S71-S76.

61. Stolzing A., Jones E., McGonagle D. et al. // Mech. Ageing Dev. 2008. Vol. 129. P. 163-173.

62. Lapasset L. et al. // Genes Dev. 2011. Vol. 25. P. 2248-2253.

63. Chen Y. S., Pelekanos R. A., Ellis R. L. et al. // Stem Cells Transl. Med. 2012. Vol. 1, N 2. P. 83-95.

64. Poloni A., Maurizi G., Leoni P. et al. // Stem Cells. 2012. Vol. 30, N 5. P. 965-974.

65. Shen J. F., Sugawara A., Yamashita J. et al. // Int. J. Oral Sci. 2011. Vol. 3, N 3. P. 117-124.

66. Geti I., Ormiston M. L., Rouhani F. et al. // Stem Cells Transl. Med. 2012. Publ. on line 29 Nov. 2012. doi:10.5966/ sctm.2012-0093.

67. Staerk J., Dawlaty M. M., Gaoet Q. et al. // Cell Stem Cell. 2010. Vol. 7, N 1. P. 20-24.

68. Park T. S., Huo J. S., Peters A. et al. // PLoS ONE. 2012. Vol. 7, N 8. e42838. doi:10.1371/journal.pone.0042838.

69. Zhou T., Benda C., Duzinger S. et al. // J. Am. Soc. Nephrol. 2011. Vol. 22. P. 1221-1228.

70. Zhou T., Benda C., Dunzinger S. et al. // Nature Protocols. 2012. Vol. 7, N 12. P. 2080-2089.

71. Polo J. M., Liu S., Figueroa M. E. et al. // Nat. Biotechnol. 2010. Vol. 28. P. 848-855.

72. Miura K., Okada Y., Aoi T. et al. // Nat. Biotechnol. 2009. Vol. 27. P. 743-745.

73. Liang Y., Zhang H., Feng Q. S. et al. // Chin. J. Cancer. 2012. doi: 10.5732/cjc.012.10065. (Epub. date: 2012-6-14).

74. Knoepfler P. S. // Stem Cells. 2009. Vol. 27, N 5. P. 1050-1056.

75. Zhou H., Wu S., Joo J. Y. et al. // Cell Stem Cell. 2009. Vol. 4. P. 381-384.

76. Gutierrez-Aranda I. et al. // Stem Cells. 2010. Vol. 28, N 9. P. 1568-1570.

77. Robert J. S. // Bioessays. 2004. Vol. 26. P. 1005-1012.

78. The Human Embryonic Stem Cell Debate // S. Holland, K. Lebacqz, L. Zoloth (eds). Cambridge, 2001.

79. The Pew Forum on Religion and Public Life, Religious Groups'Official Positions on Stem Cell Research, July 17, 2008. http: //pewforum.org/docs/?DocID=319.


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Sauchanka U.K. Human genome and new approaches in regenerative medicine. Proceedings of the National Academy of Sciences of Belarus, Medical series. 2014;(1):111-123. (In Russ.)

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