Association of serum levels of 25-hydroxyvitamin D with dental status, socio-demographic characteristics and subjective complaints in the adult population of Tashkent city
https://doi.org/10.29235/1814-6023-2025-22-3-195-204
Abstract
Vitamin D deficiency is recognized as a global pandemic. The identification of the relationship between hypovitaminosis D, dental pathology, gender and age, and social status, and subjective health complaints may be necessary for a preliminary diagnosis of hypovitaminosis D. Given the limited body of research and the importance of therapy, the main purpose of this research was to develop a method for detecting hypovitaminosis D during dental appointments based on a comprehensive assessment of the dental, gender and age, social status, patient complaints, as well as an evaluation of the diagnostic information these factors provide. The diagnostic significance and informative value of dental status, somatic characteristics, and patient complaints in the diagnosis of hypovitaminosis D have been established. When one of the predictors of hypovitaminosis D is present, the probability of detection ranges from 51.70 to 89.00 %. The detection of two or more high-intensity dental pathologies in a single patient increases this probability to 77.89–92.00 %. The combination of dental pathology with demographic characteristics increases the risk of hypovitaminosis D to 88.69‒93.00 %. The concurrent presence of characteristic complaints increases this risk to 95.00 %. A probabilistic model has been developed to evaluate the sensitivity and specificity of diagnostic tests for the presence of vitamin D deficiency without reference to laboratory research methods. A high degree of informative value of combined screening with the calculation of the risk of vitamin D deficiency has been proven
About the Authors
S. P. Rubnikovich
Belarusian State Medical University
Belarus
Belarus
Sergey P. Rubnikovich – D. Sc. (Med.), Professor, Rector
83, Dzerzhinski Ave., 220116, Minsk, Republic of Belarus
O. E. Bekjanova
Tashkent State Dental Institute
Uzbekistan
Uzbekistan
Olga Е. Bekjanova – D. Sc. (Med.), Professor, Head
of the Department
25, Sayram Str., 100170, Tashkent, Republic of Uzbekistan
J. J. Mannanov
Tashkent State Dental Institute
Uzbekistan
Uzbekistan
Javlonbek J. Mannanov – Ph. D. (Med.), senior lecturer
25, Sayram Str., 100170, Tashkent, Republic of Uzbekistan
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Review
For citations:
Rubnikovich S.P., Bekjanova O.E., Mannanov J.J. Association of serum levels of 25-hydroxyvitamin D with dental status, socio-demographic characteristics and subjective complaints in the adult population of Tashkent city. Proceedings of the National Academy of Sciences of Belarus, Medical series. 2025;22(3):195-204. (In Russ.) https://doi.org/10.29235/1814-6023-2025-22-3-195-204
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