Влияние глюкокортикоидных гормонов на функцию щитовидной железы
https://doi.org/10.29235/1814-6023-2021-18-1-117-126
Аннотация
На основании проведенного анализа данных литературы установлено, что введение экзогенных аналогов глюкокортикоидных гормонов (кортизона, гидрокортизона, кортикостерона, дексаметазона, бетаметазона и др.) приводит к изменению тиреоидной функции на всех уровнях (биосинтеза и секреции гормонов щитовидной железой, их транспорта, взаимодействия с рецепторами в органах-мишенях, биологического действия, метаболизма и экскреции), а также к влиянию на ее регуляцию как трансгипофизарно (блокирует секрецию тиреолиберина, тиреотропного гормона, кортиколиберина, соматолиберина и продукцию соматотропного гормона под влиянием послед- него), так и парагипофизарно (стимулирует образование инсулина β-инсулоцитами поджелудочной железы).
Об авторах
Е. А. Гусакова
Витебский государственный ордена Дружбы народов медицинский университет
Беларусь
Беларусь
Гусакова Елена Анатольевна – к анд. б иол. наук, доцент
пр. Фрунзе, 27, 210017, г. Витебск, Республика Беларусь
И. В. Городецкая
Витебский государственный ордена Дружбы народов медицинский университет
Беларусь
Беларусь
Городецкая Ирина Владимировна – д-р мед. наук, профессор, декан
пр. Фрунзе, 27, 210017, г. Витебск, Республика Беларусь
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Рецензия
Для цитирования:
Гусакова Е.А., Городецкая И.В. Влияние глюкокортикоидных гормонов на функцию щитовидной железы. Известия Национальной академии наук Беларуси. Серия медицинских наук. 2021;18(1):117-126. https://doi.org/10.29235/1814-6023-2021-18-1-117-126
For citation:
Gusakova E.A., Gorodetskaya I.V. Influence of glucocorticoid hormones on the thyroid gland function. Proceedings of the National Academy of Sciences of Belarus, Medical series. 2021;18(1):117-126. (In Russ.) https://doi.org/10.29235/1814-6023-2021-18-1-117-126
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