Применение маркеров активации и дегрануляции базофилов для диагностики пыльцевой аллергии
https://doi.org/10.29235/1814-6023-2018-15-4-405-413
Аннотация
В настоящее время известно несколько маркеров активации и дегрануляции базофилов, применяемых в тесте активации базофилов, однако активно используются лишь CD63 и CD203c. С учетом возможности использования и клинической значимости в работе изучены маркеры активации и дегрануляции CD11b, CD13, CD63, CD69, CD107a, CD164, CD203c и CD300a. Показано, что маркер дегрануляции CD107a и маркер активации CD11b обладают высокой чувствительностью и специфичностью и могут применяться для диагностики гиперчувствительности к пыльцевым аллергенам.
Об авторах
И. В. РомановаБеларусь
науч. сотрудник
А. Е. Гончаров
Беларусь
канд. мед. наук, директор
Н. И. Дударева
Беларусь
канд. мед. наук, заведующий отделением
Список литературы
1. Basophil activation testing in diagnosis and monitoring of allergic disease – an overview / B. Eberlein [et al.] // Allergo J. Inter. – 2016. – Vol. 25, N 4. – P. 106–113. https://doi.org/10.1007/s40629-016-0116-2
2. Battye, F. Flow cytometry Consulting [Electronic resource] / F. Battye. – Mode of access : http://www.frankbattye. com.au/Weasel/index.html. – Date of access : 19.06.2016.
3. Fawcett, T. An introduction to ROC analysis / T. Fawcett // Pattern Recogn. Lett. – 2006. – Vol. 27, N 8. – P. 861–874. https://doi.org/10.1016/j.patrec.2005.10.010
4. Eusebi, P. Diagnostic accuracy measures / P. Eusebi // Cerebrovasc. Dis. – 2013. – Vol. 36, N 4. – P. 267–272. https://doi.org/10.1159/000353863
5. Романова, И. В. Оптимизация условий проведения теста активации базофилов / И. В. Романова, А. Е. Гончаров, Н. И. Дударева // Вес. Нац. акад. навук Беларусi. Сер. мед. навук. – 2017. – № 4. – С. 48–59.
6. Flow-assisted allergy diagnosis: current application and future perspectives / D. G. Ebo [et al.] // Allergy. – 2006. – Vol. 61, N 9. – P. 1028–1039. https://doi.org/10.1111/j.1398-9995.2006.01039.x
7. Syk deficiency in nonreleaser basophils / C. L. Kepley [et al.] // J. Allergy Clin. Immunol. – 1999. – Vol. 104, N 2. – P. 279–284. https://doi.org/10.1016/s0091-6749(99)70367-2
8. Романова, И. В. Оптимизация алгоритма гейтирования базофилов на проточном цитометре: многоцветный анализ / И. В. Романова, А. Е. Гончаров, Н. И. Дударева // Вес. Нац. акад. навук Беларусi. Сер. мед. навук. – 2016. – № 4. – С. 15–24.
9. Basophil activation during pollen season in patients monosensitized to grass pollens / M. Saporta [et al.] // Allergy. – 2001. – Vol. 56, N 5. – P. 442–445. https://doi.org/10.1034/j.1398-9995.2001.056005442.x
10. Utility of laboratory testing for the diagnosis of Hymenoptera venom allergy / M. Vachová [et al.] // Allergy Asthma Proc. – 2016. – Vol. 37, N 3. – P. 248–255. https://doi.org/10.2500/aap.2016.37.3934
11. Flow-cytometric basophil activation test by detection of CD63 expression in patients with immediate-type reactions to betalactam antibiotics / M. L. Sanz [et al.] // Clin. Exp. Allergy. – 2002. – Vol. 32, N 2. – P. 277–286. https://doi.org/10.1046/ j.1365-2222.2002.01305.x
12. Human basophil activation measured by CD63 expression and LTC4 release in IgE-mediated food allergy / D. A. Moneret-Vautrin [et al.] // Ann. Allergy Asthma Immunol. – 1999. – Vol. 82, N 1. – P. 33–40. https://doi.org/10.1016/ s1081-1206(10)62657-9
13. Identification of CD13, CD107a, and CD164 as novel basophil-activation markers and dissection of two response patterns in time kinetics of IgE-dependent upregulation / F. Hennersdorf [et al.] // Cell Res. – 2005. – Vol. 15, N 5. – P. 325–335. https://doi.org/10.1038/sj.cr.7290301
14. Grass pollen allergen-induced surface expression of CD203C, CD63 and CD107A on CRTH2+ basophils: novel biomarkers for monitoring efficacy of allergen-specific immunotherapy / M. Shamji [et al.] // World Allergy Organ. J. – 2012. – Vol. 5, suppl. 2. – P. S49. https://doi.org/10.1097/01.WOX.0000411842.94409.90
15. Bühring, H. J. The basophil-specific ectoenzyme E-NPP3 (CD203c) as a marker for cell activation and allergy diagnosis / H. J. Bühring, A. Streble, P. Valent // Int. Arch. Allergy Immunol. – 2004. – Vol. 133, N 4. – P. 317–329. https://doi.org/10.1159/000077351
16. Comparison of basophil activation tests using CD63 or CD203c expression in patients with insect venom allergy / B. Eberlein-König [et al.] // Allergy. – 2006. – Vol. 61, N 9. – P. 1084–1085. https://doi.org/10.1111/j.1398-9995.2006.01122.x
17. Comparison of two basophil activation markers CD63 and CD203c in the diagnosis of amoxicillin allergy / N. Abuaf [et al.] // Clin. Exp. Allergy. – 2008. – Vol. 38, N 6. – P. 921–928. https://doi.org/10.1111/j.1365-2222.2008.02960.x
18. Marked improvement of the basophil activation test by detecting CD203c instead of CD63 / R. Boumiza [et al.] // Clin. Exp. Allergy. – 2003. – Vol. 33, N 2. – P. 259–265. https://doi.org/10.1046/j.1365-2222.2003.01594.x
19. Validation of basophil CD164 upregulation for pollen allergy diagnosis / A. Wolanczyk-Medrala [et al.] // Arch. Immunol. Ther. Exp. – 2010. – Vol. 58, N 6. – P. 459–465. https://doi.org/10.1007/s00005-010-0104-z
20. The effects of dasatinib on IgE receptor-dependent activation and histamine release in human basophils / M. Kneidinger [et al.] // Blood. – 2008. – Vol. 111, N 6. – P. 3097–3107. https://doi.org/10.1182/blood-2007-08-104372
21. Recombinant allergens promote expression of aminopeptidase-n (CD13) on basophils in allergic patients / K. Sonneck [et al.] // Int. J. Immunopathol. Pharmacol. – 2008. – Vol. 21, N 1. – P. 11–21. https://doi.org/10.1177/039463200802100103
22. Activation markers of human basophils: CD69 expression is strongly and preferentially induced by IL-3 / C. Yoshimura [et al.] // J. Allergy Clin. Immunol. – 2002. – Vol. 109, N 5. – P. 817–823. https://doi.org/10.1067/mai.2002.123532
23. Bochner, B. S. Altered surface expression of CD11 and Leu 8 during human basophil degranulation / B. S. Bochner, S. A. Sterbinsky // J. Immunol. – 1991. – Vol. 146, N 7. – P. 2367–2373.
24. Effects of prostaglandin D(2) and 5-lipoxygenase products on the expression of CD203c and CD11b by basophils / G. Monneret [et al.] // J. Pharmacol. Exp. Ther. – 2005. – Vol. 312, N 2. – P. 627–634. https://doi.org/10.1124/jpet.104.074823
25. MacGlashan Jr., D. Marked differences in the signaling requirements for expression of cd203c and cd11b versus cd63 expression and histamine release in human basophils / D. MacGlashan Jr. // Int. Arch. Allergy Immunol. – 2012. – Vol. 159, N 3. – P. 243–252. https://doi.org/10.1159/000332150
26. Human basophils express the inhibitory receptor CD300a (IRp60) / V. Sabato [et al.] // J. Allergy Clin. Immunol. – 2011. – Vol. 127, N 2. – P. AB75. https://doi.org/10.1016/j.jaci.2010.12.310
27. Mechanism of phosphatidylserine inhibition of IgE/FcεRI-dependent anaphylactic human basophil degranulation via CD300a / V. Sabato [et al.] // J. Allergy Clin. Immunol. – 2014. – Vol. 134, N 3. – P. 734–737. https://doi.org/10.1016/ j.jaci.2014.03.029
Рецензия
Для цитирования:
Романова И.В., Гончаров А.Е., Дударева Н.И. Применение маркеров активации и дегрануляции базофилов для диагностики пыльцевой аллергии. Известия Национальной академии наук Беларуси. Серия медицинских наук. 2018;15(4):405-413. https://doi.org/10.29235/1814-6023-2018-15-4-405-413
For citation:
Ramanava I.U., Hancharou A.Y., Dudarava N.I. Application of basophil activation and degranulation markers for diagnosis of pollen allergy. Proceedings of the National Academy of Sciences of Belarus, Medical series. 2018;15(4):405-413. (In Russ.) https://doi.org/10.29235/1814-6023-2018-15-4-405-413