MORPHOFUNCTIONAL DISORDERS IN THE HIPPOCAMPUS AT ANTENATAL ALCOHOLIZATION
https://doi.org/10.29235/1814-6023-2018-15-1-119-125
Abstract
The review summarizes the literature data on hippocampus morphofunctional disorders that which arise under the action of antenatal alcoholization. The hippocampus is located deep in the cerebral hemispheres, is part of the temporal lobe, belongs to the olfactory brain and consists of tightly packed cells in the ribbon structure that extend along the medial walls of the lower horns of the lateral ventricles of the brain in the anteroposterior direction. One of the classifications refers the hippocampus along with the olfactory cortex to the ancient cortex (archcortex), and the other – to the old (paleocortex). Prenatal alcoholization leads to the fact that a number of specific disorders develop in the fetus. They are integrated into the concept of the fetal alcohol syndrome (FAS) entering the “fetal alcohol spectrum disorders” (FASD). The hippocampus is one of the regions of the brain most vulnerable to the ethanol effects. The literature contains numerous data on various morphological disorders in the hippocampus of people and animals who have suffered from the antenatal alcoholization: from anatomical to subcellular and molecular. They can underlie brain abnormalities, neurological, behavioral and psychiatric disorders observed when the fetus is exposed to alcohol.
About the Authors
Sergey M. Zimatkin
Grodno State Medical University
Belarus
Belarus
D. Sc. (Biol.), Head of the Department
80, Gorky Str., 230015, Grodno
Lizaveta I. Bon
Grodno State Medical University
Belarus
Belarus
Assistant
80, Gorky Str., 230015, Grodno
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Review
For citations:
Zimatkin S.M., Bon L.I. MORPHOFUNCTIONAL DISORDERS IN THE HIPPOCAMPUS AT ANTENATAL ALCOHOLIZATION. Proceedings of the National Academy of Sciences of Belarus, Medical series. 2018;15(1):119-125. (In Russ.) https://doi.org/10.29235/1814-6023-2018-15-1-119-125
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