DISTURBANCE OF BRAIN WATER METABOLISM IN TUMORS OF DIFFERENT-DEGREE MALIGNANCY
Abstract
The methods of functional magnetic resonance imaging have been used to study the brain water exchange in tumors of different-degree malignancy. The studies were performed in the phase-contrast T2 -weighted mode and the diffusionweighted mode. Data were obtained on the distribution of peritumoral edema, water mobility in the edema and parenchyma of the brain, the movement of cerebrospinal fluid in the Sylvian aqueduct. A positive correlation (R = 96 %) was found between the amount of peritumoral edema and the asymmetry coefficient value. The obtained data of water metabolism of the brain are difficult to explain from the classical point of view. A new approach based on the participation of the brain parenchyma capillaries provides better opportunities for interpreting the obtained results.
About the Authors
L. P. Parkhach
Republican Research and Practical Center of Neurology and Neurosurgery
Belarus
Ph. D. (Biol.), Assistant Professor, Scientific Secretary
Belarus
Ph. D. (Biol.), Assistant Professor, Scientific Secretary
R. G. Ashurov
Republican Research and Practical Center of Neurology and Neurosurgery
Belarus
Ph. D. (Med.),, doctorate thesis researcher
Belarus
Ph. D. (Med.),, doctorate thesis researcher
A. F. Smeyanovich
Republican Research and Practical Center of Neurology and Neurosurgery
Belarus
Academician, D. Sc. (Med.), Professor, Head of the Department
Belarus
Academician, D. Sc. (Med.), Professor, Head of the Department
E. P. Titovets
Republican Research and Practical Center of Neurology and Neurosurgery
Belarus
D. Sc. (Biol.), Professor, Chief researcher
Belarus
D. Sc. (Biol.), Professor, Chief researcher
K. V. Bosyakova
Republican Research and Practical Center of Neurology and Neurosurgery
Belarus
Researcher
Belarus
Researcher
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Review
For citations:
Parkhach L.P., Ashurov R.G., Smeyanovich A.F., Titovets E.P., Bosyakova K.V. DISTURBANCE OF BRAIN WATER METABOLISM IN TUMORS OF DIFFERENT-DEGREE MALIGNANCY. Proceedings of the National Academy of Sciences of Belarus, Medical series. 2017;(3):111-120. (In Russ.)
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