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MOLECULAR EPIDEMIOLOGY OF ENTEROVIRUSES CAUSING SEVERE NEUROLOGICAL INFECTION FORMS

Abstract

The study analyzes the molecular epidemiology of enteroviruses that caused severe neurologic forms of infection in Belarus in 2016. The obtained results showed the predominating role of Echovirus 9 among the etiologic agents of enteroviral meningitis in 2016. The identified isolates of ECHO 9 revealed significant genetic heterogeneity: they belonged to 3 different genogroups and 4 genovariants. Two of the three genogroups of Echovirus 9 (L and K) were not previously described, and the circulation of the genogroup ω in Eurasia was not previously registered. The results testify to the important role of molecular epidemiology in the surveillance system of non-polio enteroviruses.

About the Authors

N. V. Paklonskaya
Republican Research and Practical Center for Epidemiology and Microbiology
Belarus
Ph. D. (Biol.), Leading researcher


T. V. Amvrosieva
Republican Research and Practical Center for Epidemiology and Microbiology
Belarus
D. Sc. (Med.), Professor, Head of the Laboratory


S. K. Lozuk
Republican Research and Practical Center for Epidemiology and Microbiology
Belarus
Junior researcher


Y. A. Shilova
Republican Research and Practical Center for Epidemiology and Microbiology
Belarus
Junior researcher


Z. F. Bogush
Republican Research and Practical Center for Epidemiology and Microbiology
Belarus
Researcher


N. M. Biskina
Republican Center for Hygiene, Epidemiology and Public Health
Belarus
Epidemiologist


References

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Review

For citations:


Paklonskaya N.V., Amvrosieva T.V., Lozuk S.K., Shilova Y.A., Bogush Z.F., Biskina N.M. MOLECULAR EPIDEMIOLOGY OF ENTEROVIRUSES CAUSING SEVERE NEUROLOGICAL INFECTION FORMS. Proceedings of the National Academy of Sciences of Belarus, Medical series. 2017;(3):29-36. (In Russ.)

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ISSN 1814-6023 (Print)
ISSN 2524-2350 (Online)