Структурно-функциональные особенности Nox2-НАД(Ф)Н-оксидазы
Аннотация
В контексте развития направлений разработки способов и средств управления редокс-зависимыми процессами в организме человека в настоящей работе отражены как история развития научных представлений об одном из важнейших биологических генераторов активных форм кислорода - №ж2-НАДФН-оксидазе (К.Ф.1.6.3.1, Nox2), так и современный взгляд на особенности локализации и молекулярного строения этого ферментного комплекса, а также на спектр и биологическое значение активных форм кислорода, генерируемых при его участии.
Ключевые слова
активные формы кислорода,
Nox2-НАДФН-оксидаза,
редокс-регуляция,
K.Ф.1.6.3.1,
Nox2,
,
,
,
reactive oxygen species,
Nox2-NADPH oxidase,
redox regulation E.C.1.6.3.1,
Nox2,
,
,
Список литературы
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Рецензия
Для цитирования:
Бизунок Н.А. Структурно-функциональные особенности Nox2-НАД(Ф)Н-оксидазы. Известия Национальной академии наук Беларуси. Серия медицинских наук. 2016;(1):117-128.
For citation:
Bizunok N.A. Structural and functional features of Nox2-NAD(P)H-oxidase. Proceedings of the National Academy of Sciences of Belarus, Medical series. 2016;(1):117-128. (In Russ.)
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