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Structural features of the jejunum of rats developing in the conditions of mother cholestasis and the effects of ursodeoxycholic acid

Abstract

In the experiments on 76 rat pups 15-, 45- and 90-day-old using a complex of morphological and functional methods, it was found that cholestasis of pregnancy inhibits the development of the offspring born from structural and cytochemical properties of the jejunum. The use of experimental female rats of ursodeoxycholic acid (UDCA) reduces the severity of these changes in the offspring in all terms of study.

About the Authors

Ya. R. Matsiuk
Grodno State Medical University
Belarus


Y. N. Chernyshevich
Grodno State Medical University
Belarus


References

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Review

For citations:


Matsiuk Ya.R., Chernyshevich Y.N. Structural features of the jejunum of rats developing in the conditions of mother cholestasis and the effects of ursodeoxycholic acid. Proceedings of the National Academy of Sciences of Belarus, Medical series. 2016;(1):78-85. (In Russ.)

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ISSN 1814-6023 (Print)
ISSN 2524-2350 (Online)