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Proceedings of the National Academy of Sciences of Belarus, Medical series

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Clinical and morphological analysis of inflammatory breast cancer

Abstract

We analyzed the primary medical documentation of 192 patients with the established in 2009-2013 diagnosis "breast cancer stage cT4N0-3M0". There were statistically significant differences in overall and progression-free survival depending on both the degree of involved regional lymph nodes (cN0-2 vs cN3) and the use of surgery and radiotherapy (p < 0.05). Statistically significant differences in progression-free (p = 0.022), but not in overall survival (p = 0.971) according to use/no use of neoadjuvant chemotherapy were identified. The objective response to neoadjuvant chemotherapy with the inclusion of anthracycline was influenced by the hormone-receptor status, as well as by the molecular genetic subtype (p < 0.05), but not by the histologic characteristics of the tumor (p > 0.05).

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Tratsiak I.Y., Demidchik Y.E., Kostiuk S.A. Clinical and morphological analysis of inflammatory breast cancer. Proceedings of the National Academy of Sciences of Belarus, Medical series. 2016;(1):4-10. (In Russ.)

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ISSN 1814-6023 (Print)
ISSN 2524-2350 (Online)