Participation of cholino- and adrenoreactive systems in mechanisms of development of cardioprotective effects of remote ischemic pre- and postconditioning in old rats
Abstract
The aim of this study was to determine the participation of M-cholino- and β-adrenoreactive systems in mechanisms of development of cardioprotective effects of phenomena of remote ischemic pre- and postconditioning in old rats. It was found that the activity of M-cholino- and β-adrenoreactive systems did not play a significant role in mechanisms of development of the antiischemic effect of phenomena of remote ischemic pre- and postconditioning in old rats. Administration of metoprolol before remote ischemic preconditioning enhances the antiarrhythmic effect of phenomena of remote ischemic preconditioning in old rats.
About the Authors
P. F. Jushkevich
Belarusian State Medical University
Belarus
Belarus
F. I. Vismont
Belarusian State Medical University
Belarus
Belarus
A. G. Mrochek
Republican Scientific Practical Center "Cardiology"
Belarus
Belarus
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Review
For citations:
Jushkevich P.F., Vismont F.I., Mrochek A.G. Participation of cholino- and adrenoreactive systems in mechanisms of development of cardioprotective effects of remote ischemic pre- and postconditioning in old rats. Proceedings of the National Academy of Sciences of Belarus, Medical series. 2015;(1):12-20. (In Russ.)
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