The immunomodulatory properties of fresh isolated uncultivated bone marrow mononuclear cells (BMMNC) were estimated. Revealed BMMNC expressed in vitro and in vivo antiproliferative effects on mitogen-stimulated rat splenocytes comparable with the mesenchymal stem cells immunosuppression, which offers the challenge of the BMMNC application in therapy of acute conditions with an inflammatory component including acute ischemic nephropathy for preventing ischemic organs affection long-term effects.

клеточная терапия, мононуклеары костного мозга, острая ишемическая нефропатия, спленоциты, cell therapy, bone marrow mononuclear cells, acute ischemic nephropathy, sple

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