Preview

Proceedings of the National Academy of Sciences of Belarus, Medical series

Advanced search

Of human culture-expanded mesenchymal stem cellsfor repair of cartilage defects

Abstract

A scientific overview of the publications on mesenchymal stem cells (MSCs) in vitro and their further application for the repair of articular cartilage defects is presented. Consideration is made of various conditions to generate the biocomposition with MSC for clinical use: the degree of MSC differentiation in the chondrogenic direction, most effective scaffolds for MSCs, an optimal cocktail of cytokines and hormones for chondrogenesis in vitro initiating and inducing the synthesis of collagen II and proteoglycans in the cells for the formation of hyaline cartilage.

For citations:


, , Of human culture-expanded mesenchymal stem cellsfor repair of cartilage defects. Proceedings of the National Academy of Sciences of Belarus, Medical series. 2014;(4):109-114. (In Russ.)

Views: 348


Creative Commons License
This work is licensed under a Creative Commons Attribution 4.0 License.


ISSN 1814-6023 (Print)
ISSN 2524-2350 (Online)