Histological changes of the brain cortex of 45 old day rats after the prenatal ethanol exposure

Abstract

Prenatal alcohol leads to the development of a number of specific fetus disorders united in the concept of fetal alcohol syndrome (FAS), which is the “spectrum fetus disorders caused by alcohol” (fetal alcohol spectrum disorders, FASD). Antenatal alcoholism causes a decrease in the thickness of the studied departments of the brain cortex, especially the parietal one, reducing the number of neurons of the 5th cortex layer (especially in the parietal cortex), an increase in the content of hyperchromic contracted, hypochromic neurons and cell-shadows in all investigated departments of the cortex.