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Proceedings of the National Academy of Sciences of Belarus, Medical series

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Capabilities of diffusion-suspended magnetic resonance imaging and positron emission tomography for early prediction of the chemotherapy effectiveness of lymphomas

Abstract

The article outlines the principles of diffusion-weighted magnetic resonance imaging (DWI) and positron emission tomography (PET) and compares the potentialities of the both diagnostic techniques for early prediction of the effectiveness of treatment of lymphomas. In contrast to other tomographic methods such as computed tomography, ultrasonography and conventional magnetic resonance imaging, DWI and PET use unique pathophysiological characteristics of malignant tumors, namely, water molecule diffusion and glucose metabolism, which allows one to diagnose on a cellular level. Increasing evidence indicates the prognostic role of early PET in lymphoma. DWI is a new very promising method for early assessment and prediction of the effectiveness of treatment of lymphomas. Because of its non-irradiative, non-invasive nature and a lower cost it may become an alternative to PET in the future.

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Kharuzhyk S.A., Zhavrid E.A., Karman A.V. Capabilities of diffusion-suspended magnetic resonance imaging and positron emission tomography for early prediction of the chemotherapy effectiveness of lymphomas. Proceedings of the National Academy of Sciences of Belarus, Medical series. 2014;(2):107-120. (In Russ.)

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ISSN 1814-6023 (Print)
ISSN 2524-2350 (Online)