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Proceedings of the National Academy of Sciences of Belarus, Medical series

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Assessment of the individual sensitivity to levothyroxine therapy

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Abstract

; the LT-4 median dose of 2.8 μg/kg). The serum total thyroxine level was more frequently elevated in women than in men (51.1 % vs. 29.2 %). An elevated free triiodothyronine level was observed more frequently in men, as compared to women (20.8 % vs. 7.8 %). The elevated FT3 levels and the FT4/FT3 ratio lower than 5 can be suggested as a reason to change a levothyroxine dose (i.e., its reduction) when the patient is not in the group for high risk of thyroid cancer recurrence and progression.

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Mityukova T.A., Akulevich N.M., Leonova T.A., Platonova T.Yu., Kohan S.B., Mankovskaya S.V., Kravchuk V.G. Assessment of the individual sensitivity to levothyroxine therapy. Proceedings of the National Academy of Sciences of Belarus, Medical series. 2014;(2):81-89. (In Russ.)

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ISSN 1814-6023 (Print)
ISSN 2524-2350 (Online)