vestimИзвестия Национальной академии наук Беларуси. Серия медицинских наукProceedings of the National Academy of Sciences of Belarus, Medical series1814-60232524-2350The Republican Unitary Enterprise Publishing House "Belaruskaya Navuka"10.29235/1814-6023-2023-20-1-34-41vestim-890Research ArticleКЛИНИЧЕСКАЯ И ЭКСПЕРИМЕНТАЛЬНАЯ МЕДИЦИНАCLINICAL AND EXPERIMENTAL MEDICINEКлиническое течение, исход и осложнения у вакцинированных пациентов с COVID-19 инфекцией, находившихся на стационарном леченииIn-hospital clinical course, outcome and complications among patients vaccinated against COVID-19КаленчицТ. И.KalenchicT. I.

Каленчиц Тамара Ивановна – канд. мед. наук, доцент

пр. Дзержинского, 83, 220116, г. Минск, Республика Беларусь

Tamara I. Kalenchic – Ph. D. (Med.), Associate Professor

83, Dzerzhinski Ave., 220116, Minsk

kalenchic@gmail.comКабакС. Л.KabakS. L.

Кабак Сергей Львович – д-р мед. наук, профессор, заведующий кафедрой

пр. Дзержинского, 83, 220116, г. Минск

Sergey L. Kabak – D. Sc. (Med.), Professor, Head of the Department

83, Dzerzhinski Ave., 220116, Minsk

kabakmorph@gmail.comЛосевичО. В.LosevichO. V.

Лосевич Ольга Валерьевна – заведующий приемным отделением

ул. Уральская, 5, 220037, г. Минск

Olga V. Losevich – Head of the Emergency Department

5, Ural’skaya Str., 220037, Minsk

lyudchik1982@gmail.comГлазкинаМ. А.GlazkinaM. A.

Глазкина Маргарита Александровна – врач приемного отделения

ул. Уральская, 5, 220037, г. Минск

Margarita A. Glazkina – Doctor of the Emergency Department

5, Ural’skaya Str., 220037, Minsk

rita.tex25@gmail.comБелорусский государственный медицинский университетBelarusian State Medical University6-я городская клиническая больница г. Минска6th City Clinical Hospital2023020320232013441Copyright © Каленчиц Т.И., Кабак С.Л., Лосевич О.В., Глазкина М.А., 20232023Каленчиц Т.И., Кабак С.Л., Лосевич О.В., Глазкина М.А.Kalenchic T.I., Kabak S.L., Losevich O.V., Glazkina M.A.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://vestimed.belnauka.by/jour/article/view/890

Проведен ретроспективный анализ историй болезни 403 пациентов, привитых вакцинами Vero Cell или «Спутник V», которые были госпитализированы в учреждение здравоохранения «6-я городская клиническая больница» г. Минска в период с 1 января по 28 февраля 2022 г. с основным диагнозом «коронавирусная инфекция (COVID-19)», подтвержденным результатами ПЦР-теста или теста на антиген вируса SARS-CoV-2, а также данными компьютерной томографии органов грудной клетки.

Полученные нами данные свидетельствуют о том, что среди лиц, инфицированных вирусом SARS-CoV-2 и госпитализированных в начале 2022 г., в разгар волны пандемии, обусловленной широким распространением омикрон-штамма вируса, преобладали пациенты в возрасте 65 лет и старше. Болезнь в 91,8 % случаев имела среднетяжелое клиническое течение. Более половины пациентов получали кислородную поддержку. Относительно небольшое их число, всего 8 (1,9 %) человек, было госпитализировано в отделение анестезиологии и реанимации, а 4 из них нуждались в механической вентиляции легких. У всех пациентов этого отделения была коморбидная патология и констатирована высокая внутрибольничная летальность (62,5 %). В структуре сопутствующей хронической патологии у всех лиц, находившихся на стационарном лечении, преобладали гипертоническая болезнь и ожирение (74,2 и 24,3 % соответственно). Среди пациентов отделений терапевтического профиля отмечены относительно небольшая продолжительность пребывания в стационаре, а также низкие внутрибольничная летальность (0,5 %) и число случаев развития осложнений (5,3 %).

This retrospective case-series analysis evaluated 403 fully vaccinated with Vero Cell or Sputnik V vaccines patients hospitalized in the 6th City Clinical Hospital of Minsk in the period between January 01 and February 28, 2022 with the main diagnosis of “coronavirus infection (COVID-19)”. The diagnosis was confirmed by PCR or SARS-CoV-2 virus antigen tests, as well as chest computed tomography data.

The study revealed higher prevalence of older patients (over 65 years) infected with the SARS-CoV-2 virus and hospitalized in early 2022, at the height of the wave of the pandemic due to the spread of the Omicron variant. Most patients (91.8 %) had moderate symptoms. More than half of them received oxygen support. A relatively small number of inpatient, only 8 persons (1.9 %), were hospitalized in the intensive care unit (ICU) and four of them needed mechanical ventilation. Comorbid conditions and high incidence of mortality (63.5 %) were common in ICU patients. Hypertension and obesity prevailed in the structure of comorbid pathology of all inpatient persons (74.2 and 24.3 %, respectively). Patients of therapeutic departments had relatively short length of stay in the hospital, as well as low in-hospital mortality (0.5 %) and low incidence of complications (5.3 %).

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The authors declare that there are no conflicts of interest present.