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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">vestim</journal-id><journal-title-group><journal-title xml:lang="ru">Известия Национальной  академии наук Беларуси. Серия медицинских наук</journal-title><trans-title-group xml:lang="en"><trans-title>Proceedings of the National Academy of Sciences of Belarus, Medical series</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1814-6023</issn><issn pub-type="epub">2524-2350</issn><publisher><publisher-name>The Republican Unitary Enterprise Publishing House "Belaruskaya Navuka"</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.29235/1814-6023-2020-17-1-20-27</article-id><article-id custom-type="elpub" pub-id-type="custom">vestim-656</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>КЛИНИЧЕСКАЯ И ЭКСПЕРИМЕНТАЛЬНАЯ МЕДИЦИНА</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>CLINICAL AND EXPERIMENTAL MEDICINE</subject></subj-group></article-categories><title-group><article-title>Морфологические изменения костной ткани вокруг дентальных имплантатов после воздействия низкочастотным ультразвуком низкой интенсивности</article-title><trans-title-group xml:lang="en"><trans-title>Morphological changes in the bone tissue around dental implants after low-frequency low-intensity ultrasound applications</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Рубникович</surname><given-names>С. П.</given-names></name><name name-style="western" xml:lang="en"><surname>Rubnikovich</surname><given-names>S. P.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Рубникович Сергей Петрович – доктор медицинских наук, профессор, заведующий кафедрой</p><p>ул. П. Бровки, 3/3, 220013, г. Минск</p><p> </p></bio><bio xml:lang="en"><p>Sergey P. Rubnikovich – D. Sc. (Med.), Professor, Head of the Department</p><p>3/3, Brovki Str., 220013, Minsk</p></bio><email xlink:type="simple">rubnikovich@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Хомич</surname><given-names>И. С.</given-names></name><name name-style="western" xml:lang="en"><surname>Khomich</surname><given-names>I. S.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Хомич Илья Станиславович – кандидат медицинских наук, доцент</p><p>ул. П. Бровки, 3/3, 220013, г. Минск</p><p> </p></bio><bio xml:lang="en"><p>Ilya S. Khomich – Ph. D. (Med.), Assistant Professor</p><p>3/3, Brovki Str., 220013, Minsk</p></bio><email xlink:type="simple">ilya.khomich@gmail.com</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Денисова</surname><given-names>Ю. Л.</given-names></name><name name-style="western" xml:lang="en"><surname>Denisova</surname><given-names>Yu. L.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Денисова Юлия Леонидовна – доктор медицинских   наук, профессор</p><p>пр. Дзержинского, 83, 220116, г. Минск</p></bio><bio xml:lang="en"><p>Yuliya L. Denisova – D. Sc. (Med.), Professor</p><p>83, Dzerzhinski Ave., 220116, Minsk</p></bio><email xlink:type="simple">denisova-yul@mail.ru</email><xref ref-type="aff" rid="aff-2"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Белорусская медицинская академия последипломного образования</institution></aff><aff xml:lang="en"><institution>Belarusian Medical Academy of Postgraduate Education</institution></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru"><institution>Белорусский государственный медицинский университет</institution></aff><aff xml:lang="en"><institution>Belarusian State Medical University</institution></aff></aff-alternatives><pub-date pub-type="collection"><year>2020</year></pub-date><pub-date pub-type="epub"><day>18</day><month>03</month><year>2020</year></pub-date><volume>17</volume><issue>1</issue><fpage>20</fpage><lpage>27</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Рубникович С.П., Хомич И.С., Денисова Ю.Л., 2020</copyright-statement><copyright-year>2020</copyright-year><copyright-holder xml:lang="ru">Рубникович С.П., Хомич И.С., Денисова Ю.Л.</copyright-holder><copyright-holder xml:lang="en">Rubnikovich S.P., Khomich I.S., Denisova Y.L.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://vestimed.belnauka.by/jour/article/view/656">https://vestimed.belnauka.by/jour/article/view/656</self-uri><abstract><p>В статье представлены результаты гистологического исследования морфологических изменений в костной ткани вокруг установленных дентальных имплантатов после воздействия низкоинтенсивным низкочастотным ультразвуком при дентальной имплантации. Проведены гистологические исследования блоков костной ткани вокруг установленных дентальных имплантатов, которые подвергались разным режимам ультразвукового воздействия большеберцовой кости, у лабораторных животных трех групп. В ходе исследований установлено, что процессы остеоинтеграции дентальных имплантатов у животных всех групп происходили без нарушения стадийности. На ранних сроках формировалась грануляционная ткань, которая впоследствии замещалась ретикулофиброзной костной тканью, а затем и более зрелой пластинчатой. Сроки и степень созревания костной ткани, а также показатели остеоинтеграции в группах с использованием низкоинтенсивного импульсного ультразвука и без его применения значительно отличались. Показано, что ультразвуковое воздействие на периимплантные ткани индуцирует процессы остеорепарации, стимулируя неоангиогенез в грануляционной и новообразованной костной ткани. Установлено, что ультразвуковое воздействие на имплантаты, а затем и на периимплантные ткани при дентальной имплантации способствует формированию костной ткани, гистоструктура которой схожа с гистоструктурой материнской кости в более ранние сроки.</p></abstract><trans-abstract xml:lang="en"><p>The article presents the results of a histological study of morphological changes in bone tissue around established dental implants after exposure to low-intensity, low-frequency ultrasound during dental implantation. Histological studies of tibia bone blocks were conducted in three groups of laboratory animals around installed dental implants, which were subjected to different modes of ultrasonic exposure. In the course of studies, it was found that the processes of osseointegration of dental implants in animals of all groups occurred without staging. In the early stages, granulation tissue was formed, which was subsequently replaced by reticulofibrotic bone tissue, and then by more mature lamellar tissue. The timing and degree of bone maturation, as well as the indicators of osseointegration in groups using low-intensity pulsed ultrasound and without it, were significantly different. It was shown that the ultrasound effect on peri-implant tissues induces osteoreparative processes, stimulating neoangiogenesis in granulation and newly formed bone tissue. It has been established that ultrasonic exposure of implants, and then peri-implant tissues during dental implantation, promotes the formation of bone tissue, the histostructure of which is similar to the histostructure of the maternal bone at earlier stages.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>регенерация кости</kwd><kwd>остеобласты</kwd><kwd>ультразвук низкой интенсивности</kwd><kwd>дентальные имплантаты</kwd><kwd>гистология</kwd></kwd-group><kwd-group xml:lang="en"><kwd>bone regeneration</kwd><kwd>osteoblasts</kwd><kwd>low-intensity ultrasound</kwd><kwd>dental implants</kwd><kwd>histology</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Branemark P.-I. 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