vestimИзвестия Национальной академии наук Беларуси. Серия медицинских наукProceedings of the National Academy of Sciences of Belarus, Medical series1814-60232524-2350The Republican Unitary Enterprise Publishing House "Belaruskaya Navuka"10.29235/1814-6023-2019-16-3-263-270vestim-503Research ArticleКЛИНИЧЕСКАЯ И ЭКСПЕРИМЕНТАЛЬНАЯ МЕДИЦИНАCLINICAL AND EXPERIMENTAL MEDICINEСтруктурно-функциональное состояние сердечно-сосудистой системы пациентов с инфарктом миокарда и острым ишемическим повреждением почекStructural and functional condition of the cardiovascular system in patients with myocardial infarction and acute ischaemic kidney injuryБранковскаяЕ. Ю.BrankouskayaА. Y.

Бранковская Елена Юрьевна – аспирант, врач-кардиолог

пр. Дзержинского, 83, 220116, г. Минск

Alena Y. Brankouskaya – Postgraduate student, cardiologist

83, Dzerzhinski Ave., 220116, Minsk

Lerena@yandex.ruМитьковскаяН. П.MitkovskayaN. P.

Митьковская Наталья Павловна – д-р мед. наук, профессор, заведующий кафедрой

пр. Дзержинского, 83, 220116, г. Минск

Natalya P. Mitkovskaya – D. Sc. (Med.), Professor, Head of the Department

83, Dzerzhinski Ave., 220116, Minsk

Mitkovskaya1@mail.ruГуничС. В.HunichS. V.

Гунич Сергей Владимирович – заместитель главного врача

ул. Розы Люксембург, 110, 220089, г. Минск

Sergey V. Hunich – deputy chief physician

110, Rozа Liuksiemburh Str., 220089, Minsk

Gunich1983@gmail.comБелорусский государственный медицинский университетBelarusian State Medical University4-я городская клиническая больница, Минск4th Minsk Clinical Hospital201916092019163263270Copyright © Бранковская Е.Ю., Митьковская Н.П., Гунич С.В., 20192019Бранковская Е.Ю., Митьковская Н.П., Гунич С.В.Brankouskaya А.Y., Mitkovskaya N.P., Hunich S.V.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://vestimed.belnauka.by/jour/article/view/503

Согласно эпидемиологическим исследованиям, у пациентов с инфарктом миокарда (ИМ) в большом числе случаев развивается острое повреждение почек. Эта комбинация патологий прогностически неблагоприятна и требует углубленного изучения.

В статье представлен анализ результатов электрокардиографии и ультразвукового исследования сердца, а также коронароангиографии 109 пациентов в остром периоде крупноочагового ИМ. Все обследуемые были разделены на две группы. Основную группу составили пациенты, у которых течение ИМ осложнилось развитием острого ишемического повреждения почек (n = 65), группу сравнения – пациенты с ИМ и нормальной функцией почек (n = 44). Для пациентов с ИМ и острым ишемическим повреждением почек были характерны более выраженные ишемические изменения по данным электрокардиографии, большие значения размеров полости левого желудочка (ЛЖ), более выраженное снижение контрактильной функции ЛЖ, более масштабное поражение коронарного русла. У пациентов основной группы отмечались также больший удельный вес пациентов с тромботической окклюзией инфаркт-связанной артерии и большая частота встречаемости поражения в передней межжелудочковой ветви левой коронарной артерии.

According to the epidemiological studies, in patients with myocardial infarction acute kidney injury develops in the majority of cases. This combination of pathologies is prognostically unfavorable and requires an in-depth study.

The article presents the examination data of the structural and functional state of the cardiovascular system of 109 patients with acute ST-segment elevation myocardial infarction (STEMI). The studied patients were divided into two groups. The main group consisted of patients, whose myocardial infarction was complicated by the development of acute ischemic kidney injury (n = 65); the comparison group included patients with myocardial infarction and normal kidney function (n = 44). The results of electrocardiography, echocardiography and coronary angiography of the studied patients were analyzed. Patients with myocardial infarction and acute ischemic kidney injury were characterized by more pronounced ischemic changes according to electrocardiography, a more pronounced decrease in local and global contractility of the left ventricle, a larger size of the left ventricular cavity, a more frequent incidence of coronary artery multivascular lesions, a greater proportion of patients with thrombotic occlusion of the associated artery infarction and a more frequent localization of the lesion in the left anterior descending artery.

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The authors declare that there are no conflicts of interest present.