References

vestim

Известия Национальной академии наук Беларуси. Серия медицинских наук

Proceedings of the National Academy of Sciences of Belarus, Medical series

1814-60232524-2350

The Republican Unitary Enterprise Publishing House "Belaruskaya Navuka"

vestim-328

Research Article

ОБЗОРЫ

REVIEWS

НЕЙРОИНДУЦИРОВАННЫЕ МЕЗЕНХИМАЛЬНЫЕ СТВОЛОВЫЕ КЛЕТКИ В ТЕРАПИИ ЗАБОЛЕВАНИЙ НЕРВНОЙ СИСТЕМЫ

NEURO-INDUCED MESENCHYMAL STEM CELLS IN THE TREATMENT OF NERVOUS SYSTEM DISEASES

ШАХБАЗОВ

А. В.

SHAKHBAZAU

А. V.

shakhbazau@gmail.com

Университет КалгариUniversity of Calgary

2016

20112016

03107116

2016

ШАХБАЗОВ А.В.

SHAKHBAZAU А.V.

Данная работа распространяется под лицензией Creative Commons Attribution 4.0.

This work is licensed under a Creative Commons Attribution 4.0 License.

https://vestimed.belnauka.by/jour/article/view/328

Мезенхимальные стволовые клетки (МСК) рассматриваются как перспективный терапевтический агент при ряде заболеваний, включая неизлечимые патологии нервной системы. В данном обзоре обсуждается терапевтическое применение МСК, подвергнутых дифференцировке в неконвенционном нейрогенном направлении. Проведен анализ данных по нейродифференцировке МСК в культуре in vitro, результатов исследований на подопытных животных, а также последних данных клинических испытаний нейродифференцированных МСК в Беларуси и за рубежом для лечения пациентов с диагнозами «боковой амиотрофический склероз» и «эпилепсия».

Mesenchymal stem cells (MSCs) have long been viewed as a promising therapeutic agent for incurable CNS disorders. This review covers therapeutic applications of MSCs induced for a non- conventional neural differentiation. Presented are the data on MSCs neural induction in vitro, lessons from animal models, and very recent results of clinical trials with neurally induced MSCs in Belarus and worldwide in patients suffering from amyotrophic lateral sclerosis and epilepsy

мезенхимальные стволовые клетки человеканейрогенная дифференцировкабоковой амио-трофический склерозэпилепсия

human mesenchymal stem cellsneural differentiationamyotrophic lateral sclerosisepilepsy

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The authors declare that there are no conflicts of interest present.