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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">vestim</journal-id><journal-title-group><journal-title xml:lang="ru">Известия Национальной  академии наук Беларуси. Серия медицинских наук</journal-title><trans-title-group xml:lang="en"><trans-title>Proceedings of the National Academy of Sciences of Belarus, Medical series</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1814-6023</issn><issn pub-type="epub">2524-2350</issn><publisher><publisher-name>The Republican Unitary Enterprise Publishing House "Belaruskaya Navuka"</publisher-name></publisher></journal-meta><article-meta><article-id custom-type="elpub" pub-id-type="custom">vestim-317</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>КЛИНИЧЕСКАЯ И ЭКСПЕРИМЕНТАЛЬНАЯ МЕДИЦИНА</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>CLINICAL AND EXPERIMENTAL MEDICINE</subject></subj-group></article-categories><title-group><article-title>ПРОТЕИН ТИРОЗИНФОСФАТАЗЫ В ПРОГНОЗИРОВАНИИ ПЕРИТОНЕАЛЬНОЙ ДИССЕМИНАЦИИ У ПАЦИЕНТОВ С РЕЗЕКТАБЕЛЬНЫМ РАКОМ ЖЕЛУДКА</article-title><trans-title-group xml:lang="en"><trans-title>PROTEIN TYROSINE PHOSPHATASE IN THE PREDICTION OF PERITONEAL DISSEMINATION IN PATIENTS WITH RESECTABLE GASTRIC CANCER</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>РЕВТОВИЧ</surname><given-names>М. Ю.</given-names></name><name name-style="western" xml:lang="en"><surname>REUTOVICH</surname><given-names>M. Yu.</given-names></name></name-alternatives><email xlink:type="simple">mihail_revtovich@yahoo.com</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>ШМАК</surname><given-names>А. И.</given-names></name><name name-style="western" xml:lang="en"><surname>SHMAK</surname><given-names>A. I.</given-names></name></name-alternatives><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>КРАСЬКО</surname><given-names>О. В.</given-names></name><name name-style="western" xml:lang="en"><surname>KRASKO</surname><given-names>O. V.</given-names></name></name-alternatives><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>СМОЛЯКОВА</surname><given-names>Р. М.</given-names></name><name name-style="western" xml:lang="en"><surname>SMOLYAKOVA</surname><given-names>R. M.</given-names></name></name-alternatives><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Республиканский научно-практический центр онкологии и медицинской радиологии им. Н. Н. Александрова</institution></aff><aff xml:lang="en"><institution>N. N. Alexandrov National Cancer Center of Belarus</institution></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru"><institution>Объединенный институт проблем информатики НАН Беларуси</institution></aff><aff xml:lang="en"><institution>United Institute of Informatics Problems of the National Academy of Sciences of Belarus</institution></aff></aff-alternatives><pub-date pub-type="collection"><year>2016</year></pub-date><pub-date pub-type="epub"><day>19</day><month>11</month><year>2016</year></pub-date><volume>0</volume><issue>3</issue><fpage>28</fpage><lpage>34</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; РЕВТОВИЧ М.Ю., ШМАК А.И., КРАСЬКО О.В., СМОЛЯКОВА Р.М., 2016</copyright-statement><copyright-year>2016</copyright-year><copyright-holder xml:lang="ru">РЕВТОВИЧ М.Ю., ШМАК А.И., КРАСЬКО О.В., СМОЛЯКОВА Р.М.</copyright-holder><copyright-holder xml:lang="en">REUTOVICH M.Y., SHMAK A.I., KRASKO O.V., SMOLYAKOVA R.M.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://vestimed.belnauka.by/jour/article/view/317">https://vestimed.belnauka.by/jour/article/view/317</self-uri><abstract><p>Исследован уровень экспрессии гена протеин тирозинфосфатазы (PRL-3) в первичной опухоли, париетальной брюшине различных отделов брюшной полости у 52 радикально оперированных пациентов, страдающих раком желудка. Определено пороговое значение уровня экспрессии гена PRL-3, позволяющее прогнозировать прогрессирование заболевания с формированием диссеминации опухоли по брюшине после хирургического лечения.</p></abstract><trans-abstract xml:lang="en"><p>The expression level of the protein tyrosine phosphatase gene (PRL-3) in the primary tumor and parietal peritoneum of 52 radically operated gastric cancer patients was investigated. The threshold value of PRL-3 to predict the peritoneal dissemination after surgical treatment was defined.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>рак желудка</kwd><kwd>протеин тирозинфосфатазы</kwd><kwd>перитонеальная диссеминация</kwd></kwd-group><kwd-group xml:lang="en"><kwd>gastric cancer</kwd><kwd>protein tyrosine phosphatase</kwd><kwd>peritoneal dissemination</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Expression of phosphatase regenerating liver 3 is an independent prognostic indicator for gastric cancer / N. Dai [et al.] // World J. Gastroenterol. – 2009. – Vol. 15, N 12. – P. 1499–1505.</mixed-citation><mixed-citation xml:lang="en">Expression of phosphatase regenerating liver 3 is an independent prognostic indicator for gastric cancer / N. Dai [et al.] // World J. 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