vestimИзвестия Национальной академии наук Беларуси. Серия медицинских наукProceedings of the National Academy of Sciences of Belarus, Medical series1814-60232524-2350The Republican Unitary Enterprise Publishing House "Belaruskaya Navuka"vestim-311Research ArticleОБЗОРЫREVIEWSТРАНСПЛАНТАЦИЯ АУТОЛОГИЧНЫХ ГЕМОПОЭТИЧЕСКИХ СТВОЛОВЫХ КЛЕТОК ПАЦИЕНТАМ С РАССЕЯННЫМ СКЛЕРОЗОМHAEMATOPOIETIC STEM CELL TRANSPLANTATION TO PATIENTS WITH MULTIPLE SCLEROSISГичкунО. Е.GichkunO. E.Gichkunoe@yandex.ruЯрошенкоЕ. Б.YaroshenkoE. B.Gichkunoe@yandex.ruШевченкоА. О.ShevchenkoA. O.Gichkunoe@yandex.ruФедеральный научный центр трансплантологии и искусственных органов имени академика В. И. ШумаковаV. I. Shumakov Federal Research Center of Transplantology and Artificial Organs20160408201602110117Copyright © Гичкун О.Е., Ярошенко Е.Б., Шевченко А.О., 20162016Гичкун О.Е., Ярошенко Е.Б., Шевченко А.О.Gichkun O.E., Yaroshenko E.B., Shevchenko A.O.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://vestimed.belnauka.by/jour/article/view/311 

 

Рассеянный склероз (РС) – хроническое заболевание центральной нервной системы, сопровождающееся разнообразными неврологическими симптомами и в течение нескольких лет приводящее к инвалидизации. Лечение РС является одной из наиболее актуальных и сложных проблем практической медицины. Применение имеющихся на сегодняшний день препаратов позволяет лишь снизить частоту и тяжесть обострений, что для лечения хронических неврологических расстройств явно недостаточно. Трансплантация гемопоэтических клеток является одним из перспективных методов лечения РС. В обзоре представлен анализ результатов клинических исследований по применению трансплантации гемопоэтических стволовых клеток при лечении больных РС.

Multiple sclerosis (MS) is a chronic inflammatory disorder of the central nervous system leading to severe neurological deficits. Current MS treatment consists in using immunomodulatory agents aimed to reduce a rate of relapses. However, these agents are usually insufficient to treat the chronic neurological disability. The haematopoietic stem cell transplantation (HSCT) is a perspective method of MS treatment. Our review of the literature presents the information on the clinical trials of MS HSCT.

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The authors declare that there are no conflicts of interest present.