vestimИзвестия Национальной академии наук Беларуси. Серия медицинских наукProceedings of the National Academy of Sciences of Belarus, Medical series1814-60232524-2350The Republican Unitary Enterprise Publishing House "Belaruskaya Navuka"vestim-207Research ArticleКЛИНИЧЕСКАЯ И ЭКСПЕРИМЕНТАЛЬНАЯ МЕДИЦИНАCLINICAL AND EXPERIMENTAL MEDICINEМорфологическая характеристика изменений в стенке венечных артерий при атеросклеротическом пораженииMorphological characteristics of atherosclerotic lesions of the coronary artery wallКабакС. Л.KabakS. L.kabak@bsmu.byЮдинаО. А.YudinaO. A.o.yudina@inbox.ruСавошВ. В.SavoshV. V.noemail@neicon.ruБелорусский государственный медицинский университетBelarusian State Medical University9-я городская клиническая больница9th Clinical Hospital20150606201604411Copyright © Кабак С.Л., Юдина О.А., Савош В.В., 20162016Кабак С.Л., Юдина О.А., Савош В.В.Kabak S.L., Yudina O.A., Savosh V.V.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://vestimed.belnauka.by/jour/article/view/207

Материалом для исследования послужили фрагменты венечных артерий 31 пациента, умершего в больницах г. Минска и в большинстве случаев имевшего в анамнезе клинические проявления ишемической болезни сердца в сочетании с сахарным диабетом. Во всех случаях в венечных артериях были выявлены гетерогенные морфологические изменения, характерные для разных стадий развития атеросклеротического процесса, - от незначительного утолщения интимы до крупных осложненных атеросклеротических бляшек. При этом доля нестабильных атеросклеротических бляшек, склонных к разрыву, колебалась в диапазоне от 0 до 0,94 (среднее значение составило 0,44 ± 0,24). Наличие сахарного диабета в анамнезе, как правило, сопровождалось увеличением доли нестабильных атеросклеротических бляшек в венечных артериях.

There were 31 fragments of the coronary arteries investigated in patients who died in Minsk hospitals and who generally had clinical manifestations of coronary disease and diabetes mellitus. Heterogenic morphological lesions were detected in the coronary arteries which are characteristic for different stages of the atherosclerotic process from the imperceptible intima-media thickening to big complicated atherosclerotic plaques. At the same time, the fraction of the vulnerable plaques was between 0 and 0.94 (the mean value was 0.44 ± 0.24). As usual, the history of diabetes mellitus was associated with a higher quantity of unstable atherosclerotic plaques in the coronary arteries.

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