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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">vestim</journal-id><journal-title-group><journal-title xml:lang="ru">Известия Национальной  академии наук Беларуси. Серия медицинских наук</journal-title><trans-title-group xml:lang="en"><trans-title>Proceedings of the National Academy of Sciences of Belarus, Medical series</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1814-6023</issn><issn pub-type="epub">2524-2350</issn><publisher><publisher-name>The Republican Unitary Enterprise Publishing House "Belaruskaya Navuka"</publisher-name></publisher></journal-meta><article-meta><article-id custom-type="elpub" pub-id-type="custom">vestim-154</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ОБЗОРЫ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>REVIEWS</subject></subj-group></article-categories><title-group><article-title>Папиллярный рак щитовидной железы: факторы прогноза</article-title><trans-title-group xml:lang="en"><trans-title>Papillary thyroid cancer: prognostic factors</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Короткевич</surname><given-names>П. Е.</given-names></name><name name-style="western" xml:lang="en"><surname>Korotkevich</surname><given-names>P. Y.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Демидчик</surname><given-names>Ю. Е.</given-names></name><name name-style="western" xml:lang="en"><surname>Demidchik</surname><given-names>Y. E.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Гаин</surname><given-names>Ю. М.</given-names></name><name name-style="western" xml:lang="en"><surname>Gain</surname><given-names>Y. M.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Барьяш</surname><given-names>В. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Baryash</surname><given-names>V. V.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email></contrib></contrib-group><pub-date pub-type="collection"><year>2014</year></pub-date><pub-date pub-type="epub"><day>01</day><month>06</month><year>2016</year></pub-date><volume>0</volume><issue>3</issue><fpage>91</fpage><lpage>95</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Короткевич П.Е., Демидчик Ю.Е., Гаин Ю.М., Барьяш В.В., 2016</copyright-statement><copyright-year>2016</copyright-year><copyright-holder xml:lang="ru">Короткевич П.Е., Демидчик Ю.Е., Гаин Ю.М., Барьяш В.В.</copyright-holder><copyright-holder xml:lang="en">Korotkevich P.Y., Demidchik Y.E., Gain Y.M., Baryash V.V.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://vestimed.belnauka.by/jour/article/view/154">https://vestimed.belnauka.by/jour/article/view/154</self-uri><abstract><p>Во всем мире наблюдается устойчивый рост заболеваемости раком щитовидной железы (ШЗ), преимущественно за счет папиллярного рака (ПР). Существует множество обусловленных опухолевым процессом факторов, определяющих исход заболевания. Основными считаются возраст, пол, экстратиреоидное распространение опухоли, неполное удаление новообразования, размер первичного очага, перитуморальная инвазия сосудов, наличие регионарных и отдаленных метастазов, а также степень дифференциации опухоли. К настоящему времени предложен ряд систематизированных шкал: TNM, EORTC, MACIS, AMES, AGES и др. В зависимости от использованной прогностической шкалы формируются группы риска, определяющие причинно-специфическую выживаемость или вероятность наступления смерти от рака в каждой группе. Чаще неблагоприятный исход возможен у пациентов с высоким риском, у которых наблюдаются морфологические неблагоприятные варианты ПРШЗ, а также у пациентов с массивным экстратиреоидным распространением опухоли и наличием отдаленных метастазов. Хороший прогноз у пациентов с интратиреоидными опухолями, диагностированными в молодом возрасте, без регионарных и отдаленных метастазов, особенно на фоне аутоиммунного тиреоидита.</p></abstract><trans-abstract xml:lang="en"><p>Globally, there is a steady increase in the incidence of thyroid cancer, mainly due to papillary cancer. There are a lot of factors caused by neoplastic process which determine the outcome of the disease. The main considered factors are age, sex, extrathyroidal tumor expansion, incomplete removal of the tumor, the size of the primary malignancy, peritumoral vascular invasion, the presence of regional and distant metastases, as well as the degree of differentiation of the tumor. To date there is a range of systematic scales: TNM, EORTC, MACIS, AMES, AGES, etc. According to the used prognostic scale risk groups are formed which determine causal and specific survival or risk of dying from cancer in each group. More often unfavorable outcome is possible in patients at high risk who are experiencing adverse morphological variants of papillary thyroid cancer as well as in patients with a massive extrathyroidal tumor expansion and the presence of distant metastases. Patients with intrathyroid tumors diagnosed at a young age, without regional and distant metastases, have positive prognosis, especially against the background of autoimmune thyroiditis.</p></trans-abstract></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Curado M. // IARC Sci. Publ. 2007. Vol. 9, N 160.</mixed-citation><mixed-citation xml:lang="en">Curado M. // IARC Sci. Publ. 2007. Vol. 9, N 160.</mixed-citation></citation-alternatives></ref><ref id="cit2"><label>2</label><citation-alternatives><mixed-citation xml:lang="ru">Siegel R. // Cancer J. Clin. 2011. Vol. 61. P. 212-236.</mixed-citation><mixed-citation xml:lang="en">Siegel R. // Cancer J. Clin. 2011. Vol. 61. P. 212-236.</mixed-citation></citation-alternatives></ref><ref id="cit3"><label>3</label><citation-alternatives><mixed-citation xml:lang="ru">Kilfoy B. // Cancer Causes and Control. 2009. Vol. 20, N 5. P. 525-531.</mixed-citation><mixed-citation xml:lang="en">Kilfoy B. // Cancer Causes and Control. 2009. Vol. 20, N 5. P. 525-531.</mixed-citation></citation-alternatives></ref><ref id="cit4"><label>4</label><citation-alternatives><mixed-citation xml:lang="ru">Leenhardt L. // Thyroid. 2004. Vol. 14. P. 1056-1060.</mixed-citation><mixed-citation xml:lang="en">Leenhardt L. // Thyroid. 2004. Vol. 14. P. 1056-1060.</mixed-citation></citation-alternatives></ref><ref id="cit5"><label>5</label><citation-alternatives><mixed-citation xml:lang="ru">Liu S. // Br. J. Cancer. 2001. Vol. 85. P. 1335-1339.</mixed-citation><mixed-citation xml:lang="en">Liu S. // Br. J. Cancer. 2001. Vol. 85. P. 1335-1339.</mixed-citation></citation-alternatives></ref><ref id="cit6"><label>6</label><citation-alternatives><mixed-citation xml:lang="ru">Lubina A. // Thyroid. 2006. Vol. 16. P. 1033-1140.</mixed-citation><mixed-citation xml:lang="en">Lubina A. // Thyroid. 2006. Vol. 16. P. 1033-1140.</mixed-citation></citation-alternatives></ref><ref id="cit7"><label>7</label><citation-alternatives><mixed-citation xml:lang="ru">Демидчик Е. П. Рак щитовидной железы у детей. М., 1996.</mixed-citation><mixed-citation xml:lang="en">Демидчик Е. П. Рак щитовидной железы у детей. М., 1996.</mixed-citation></citation-alternatives></ref><ref id="cit8"><label>8</label><citation-alternatives><mixed-citation xml:lang="ru">Демидчик Ю. Е. // Онколог. журн. 2008. Т. 2, № 4. С. 9-21.</mixed-citation><mixed-citation xml:lang="en">Демидчик Ю. Е. // Онколог. журн. 2008. Т. 2, № 4. С. 9-21.</mixed-citation></citation-alternatives></ref><ref id="cit9"><label>9</label><citation-alternatives><mixed-citation xml:lang="ru">Демидчик Ю. Е. // Онколог. журн. 2008. Т. 2, № 3. С. 18-30.</mixed-citation><mixed-citation xml:lang="en">Демидчик Ю. Е. // Онколог. журн. 2008. Т. 2, № 3. С. 18-30.</mixed-citation></citation-alternatives></ref><ref id="cit10"><label>10</label><citation-alternatives><mixed-citation xml:lang="ru">Фридман М. В. // Мед. новости. 2008. № 9. С. 83-90.</mixed-citation><mixed-citation xml:lang="en">Фридман М. В. // Мед. новости. 2008. № 9. С. 83-90.</mixed-citation></citation-alternatives></ref><ref id="cit11"><label>11</label><citation-alternatives><mixed-citation xml:lang="ru">Кубарко А. И. Щитовидная железа: фунд. аспекты. М., 1998.</mixed-citation><mixed-citation xml:lang="en">Кубарко А. И. Щитовидная железа: фунд. аспекты. М., 1998.</mixed-citation></citation-alternatives></ref><ref id="cit12"><label>12</label><citation-alternatives><mixed-citation xml:lang="ru">Davies L. // J. A. M. A. 2002. Vol. 295, N 18. P. 2164-2167.</mixed-citation><mixed-citation xml:lang="en">Davies L. // J. A. M. A. 2002. Vol. 295, N 18. P. 2164-2167.</mixed-citation></citation-alternatives></ref><ref id="cit13"><label>13</label><citation-alternatives><mixed-citation xml:lang="ru">Grodski S. // Surgery. 2006. Vol. 144, N 6. P. 1038-1043.</mixed-citation><mixed-citation xml:lang="en">Grodski S. // Surgery. 2006. Vol. 144, N 6. P. 1038-1043.</mixed-citation></citation-alternatives></ref><ref id="cit14"><label>14</label><citation-alternatives><mixed-citation xml:lang="ru">Enewold L. // Cancer Epidemiol. Biomarkers and Prevention. 2009. Vol. 18, N 3. P. 784-791.</mixed-citation><mixed-citation xml:lang="en">Enewold L. // Cancer Epidemiol. Biomarkers and Prevention. 2009. Vol. 18, N 3. P. 784-791.</mixed-citation></citation-alternatives></ref><ref id="cit15"><label>15</label><citation-alternatives><mixed-citation xml:lang="ru">Kent W. D. et al. // Canad. Med. Association J. 2007. Vol. 177, N l. P. 1357-1361.</mixed-citation><mixed-citation xml:lang="en">Kent W. D. et al. // Canad. Med. Association J. 2007. Vol. 177, N l. P. 1357-1361.</mixed-citation></citation-alternatives></ref><ref id="cit16"><label>16</label><citation-alternatives><mixed-citation xml:lang="ru">Demidchik E. // Inter. Congr. Series. 2001. P. 69-77.</mixed-citation><mixed-citation xml:lang="en">Demidchik E. // Inter. Congr. Series. 2001. P. 69-77.</mixed-citation></citation-alternatives></ref><ref id="cit17"><label>17</label><citation-alternatives><mixed-citation xml:lang="ru">Jacob P. // Radiat. Res. 2006. Vol. 165. P. 1-8.</mixed-citation><mixed-citation xml:lang="en">Jacob P. // Radiat. Res. 2006. Vol. 165. P. 1-8.</mixed-citation></citation-alternatives></ref><ref id="cit18"><label>18</label><citation-alternatives><mixed-citation xml:lang="ru">Pellegriti G. // J. of Cancer Epidemiol. 2013. Vol. 67. P. 26-38.</mixed-citation><mixed-citation xml:lang="en">Pellegriti G. // J. of Cancer Epidemiol. 2013. Vol. 67. P. 26-38.</mixed-citation></citation-alternatives></ref><ref id="cit19"><label>19</label><citation-alternatives><mixed-citation xml:lang="ru">Williams E. // Surg. Oncol. 2006. Vol. 94. P. 670-677.</mixed-citation><mixed-citation xml:lang="en">Williams E. // Surg. Oncol. 2006. Vol. 94. P. 670-677.</mixed-citation></citation-alternatives></ref><ref id="cit20"><label>20</label><citation-alternatives><mixed-citation xml:lang="ru">Пачес А. И. Рак щитовидной железы. М., 1995.</mixed-citation><mixed-citation xml:lang="en">Пачес А. И. Рак щитовидной железы. М., 1995.</mixed-citation></citation-alternatives></ref><ref id="cit21"><label>21</label><citation-alternatives><mixed-citation xml:lang="ru">Цыб А. Ф. Ультразвуковая диагностика заболеваний щитовидной железы. М., 1997.</mixed-citation><mixed-citation xml:lang="en">Цыб А. Ф. Ультразвуковая диагностика заболеваний щитовидной железы. М., 1997.</mixed-citation></citation-alternatives></ref><ref id="cit22"><label>22</label><citation-alternatives><mixed-citation xml:lang="ru">Albores-Saavedra J. // Endocrine pathol. 2007. Vol. 18. P. 1-7.</mixed-citation><mixed-citation xml:lang="en">Albores-Saavedra J. // Endocrine pathol. 2007. Vol. 18. P. 1-7.</mixed-citation></citation-alternatives></ref><ref id="cit23"><label>23</label><citation-alternatives><mixed-citation xml:lang="ru">Thyroid Carcinoma Task Force. American Association of Clinical Endocrinologists // Endocr. Pract. 2001. Vol. 7. P. 202-220.</mixed-citation><mixed-citation xml:lang="en">Thyroid Carcinoma Task Force. American Association of Clinical Endocrinologists // Endocr. Pract. 2001. Vol. 7. P. 202-220.</mixed-citation></citation-alternatives></ref><ref id="cit24"><label>24</label><citation-alternatives><mixed-citation xml:lang="ru">Eng C. // J. Clin. Endocrinol. Metab. 2000. Vol. 85. P. 1755-1757.</mixed-citation><mixed-citation xml:lang="en">Eng C. // J. Clin. Endocrinol. Metab. 2000. Vol. 85. P. 1755-1757.</mixed-citation></citation-alternatives></ref><ref id="cit25"><label>25</label><citation-alternatives><mixed-citation xml:lang="ru">Beahrs O. American Joint Committee on Cancer Manual for Staging of Cancer. 2nd ed. M., 1983.</mixed-citation><mixed-citation xml:lang="en">Beahrs O. American Joint Committee on Cancer Manual for Staging of Cancer. 2nd ed. M., 1983.</mixed-citation></citation-alternatives></ref><ref id="cit26"><label>26</label><citation-alternatives><mixed-citation xml:lang="ru">Siironen P. // Tumor Biol. 2005. Vol. 26. P. 57-64.</mixed-citation><mixed-citation xml:lang="en">Siironen P. // Tumor Biol. 2005. Vol. 26. P. 57-64.</mixed-citation></citation-alternatives></ref><ref id="cit27"><label>27</label><citation-alternatives><mixed-citation xml:lang="ru">Witt R. // Ear Nose Throat J. 2006. Vol. 81. P. 856-863.</mixed-citation><mixed-citation xml:lang="en">Witt R. // Ear Nose Throat J. 2006. Vol. 81. P. 856-863.</mixed-citation></citation-alternatives></ref><ref id="cit28"><label>28</label><citation-alternatives><mixed-citation xml:lang="ru">Ito Y. // World J. Surg. 2007. Vol. 31. P. 838-848.</mixed-citation><mixed-citation xml:lang="en">Ito Y. // World J. Surg. 2007. Vol. 31. P. 838-848.</mixed-citation></citation-alternatives></ref><ref id="cit29"><label>29</label><citation-alternatives><mixed-citation xml:lang="ru">Kim E. // Clin. Endocrinol. 2009. Vol. 71. P. 581-586.</mixed-citation><mixed-citation xml:lang="en">Kim E. // Clin. Endocrinol. 2009. Vol. 71. P. 581-586.</mixed-citation></citation-alternatives></ref><ref id="cit30"><label>30</label><citation-alternatives><mixed-citation xml:lang="ru">Lang B. // Ann. Surg. Oncol. 2006. Vol. 14. P. 730-738.</mixed-citation><mixed-citation xml:lang="en">Lang B. // Ann. Surg. Oncol. 2006. Vol. 14. P. 730-738.</mixed-citation></citation-alternatives></ref><ref id="cit31"><label>31</label><citation-alternatives><mixed-citation xml:lang="ru">Samuel L. // Otolaryngology-Head and Neck Surg. 2012. Vol. 147, N 2. P. 221-226.</mixed-citation><mixed-citation xml:lang="en">Samuel L. // Otolaryngology-Head and Neck Surg. 2012. Vol. 147, N 2. P. 221-226.</mixed-citation></citation-alternatives></ref><ref id="cit32"><label>32</label><citation-alternatives><mixed-citation xml:lang="ru">Ito Y. // Endocrinol. J. 2009. Vol. 56. P. 177-192.</mixed-citation><mixed-citation xml:lang="en">Ito Y. // Endocrinol. J. 2009. Vol. 56. P. 177-192.</mixed-citation></citation-alternatives></ref><ref id="cit33"><label>33</label><citation-alternatives><mixed-citation xml:lang="ru">Rajoria S. // Thyroid. 2010. Vol. 20. P. 33-41.</mixed-citation><mixed-citation xml:lang="en">Rajoria S. // Thyroid. 2010. Vol. 20. P. 33-41.</mixed-citation></citation-alternatives></ref><ref id="cit34"><label>34</label><citation-alternatives><mixed-citation xml:lang="ru">Truong T. // Am. J. Epidemiol. 2005. Vol. 161. P. 1056-1065.</mixed-citation><mixed-citation xml:lang="en">Truong T. // Am. J. Epidemiol. 2005. Vol. 161. P. 1056-1065.</mixed-citation></citation-alternatives></ref><ref id="cit35"><label>35</label><citation-alternatives><mixed-citation xml:lang="ru">Vannucchi G. // Eur. J. Endocrinol. 2010. Vol. 162. P. 145-151.</mixed-citation><mixed-citation xml:lang="en">Vannucchi G. // Eur. J. Endocrinol. 2010. Vol. 162. P. 145-151.</mixed-citation></citation-alternatives></ref><ref id="cit36"><label>36</label><citation-alternatives><mixed-citation xml:lang="ru">Sakoda L. // Cancer Epidemiol. Biomarkers. Prev. 2002. Vol. 11. P. 51-57.</mixed-citation><mixed-citation xml:lang="en">Sakoda L. // Cancer Epidemiol. Biomarkers. Prev. 2002. Vol. 11. P. 51-57.</mixed-citation></citation-alternatives></ref><ref id="cit37"><label>37</label><citation-alternatives><mixed-citation xml:lang="ru">Candanedo-Gonzalez F. // Med. Hypotheses. 2007. Vol. 69. P. 209-213.</mixed-citation><mixed-citation xml:lang="en">Candanedo-Gonzalez F. // Med. Hypotheses. 2007. Vol. 69. P. 209-213.</mixed-citation></citation-alternatives></ref><ref id="cit38"><label>38</label><citation-alternatives><mixed-citation xml:lang="ru">Jonclaas J. // J. Clin. Endocrinol. Metab. 2012. Vol. 97, N 6. P. 878-887.</mixed-citation><mixed-citation xml:lang="en">Jonclaas J. // J. Clin. Endocrinol. Metab. 2012. Vol. 97, N 6. P. 878-887.</mixed-citation></citation-alternatives></ref><ref id="cit39"><label>39</label><citation-alternatives><mixed-citation xml:lang="ru">Sobin L. TNM Classification of Malignant Tumours. 6th ed. M., 2002.</mixed-citation><mixed-citation xml:lang="en">Sobin L. TNM Classification of Malignant Tumours. 6th ed. M., 2002.</mixed-citation></citation-alternatives></ref><ref id="cit40"><label>40</label><citation-alternatives><mixed-citation xml:lang="ru">Machens A. // Cancer. 2005. Vol. 103. P. 2269-2273.</mixed-citation><mixed-citation xml:lang="en">Machens A. // Cancer. 2005. Vol. 103. P. 2269-2273.</mixed-citation></citation-alternatives></ref><ref id="cit41"><label>41</label><citation-alternatives><mixed-citation xml:lang="ru">Mazzaferri E. // J. of Clin. Endocrinol. and Metabolism. 2001. Vol. 86. P. 1447-1463.</mixed-citation><mixed-citation xml:lang="en">Mazzaferri E. // J. of Clin. Endocrinol. and Metabolism. 2001. Vol. 86. P. 1447-1463.</mixed-citation></citation-alternatives></ref><ref id="cit42"><label>42</label><citation-alternatives><mixed-citation xml:lang="ru">Verburg A. // Clin. Endocrinol. 2009. Vol. 71. P. 291-297.</mixed-citation><mixed-citation xml:lang="en">Verburg A. // Clin. Endocrinol. 2009. Vol. 71. P. 291-297.</mixed-citation></citation-alternatives></ref><ref id="cit43"><label>43</label><citation-alternatives><mixed-citation xml:lang="ru">Kramer J. // Eur. J. of Endocrinol. 2010. Vol. 163. P. 637-644.</mixed-citation><mixed-citation xml:lang="en">Kramer J. // Eur. J. of Endocrinol. 2010. Vol. 163. P. 637-644.</mixed-citation></citation-alternatives></ref><ref id="cit44"><label>44</label><citation-alternatives><mixed-citation xml:lang="ru">Ortiz S. // Otolaryngol. Head Neck Surg. 2001. Vol. 124. P. 261-265.</mixed-citation><mixed-citation xml:lang="en">Ortiz S. // Otolaryngol. Head Neck Surg. 2001. Vol. 124. P. 261-265.</mixed-citation></citation-alternatives></ref><ref id="cit45"><label>45</label><citation-alternatives><mixed-citation xml:lang="ru">Ito Y. // World J. Surg. 2006. Vol. 30. P. 1821-1828.</mixed-citation><mixed-citation xml:lang="en">Ito Y. // World J. Surg. 2006. Vol. 30. P. 1821-1828.</mixed-citation></citation-alternatives></ref><ref id="cit46"><label>46</label><citation-alternatives><mixed-citation xml:lang="ru">Nixon I. // Surgery. 2011. Vol. 150. P. 1242-1249.</mixed-citation><mixed-citation xml:lang="en">Nixon I. // Surgery. 2011. Vol. 150. P. 1242-1249.</mixed-citation></citation-alternatives></ref><ref id="cit47"><label>47</label><citation-alternatives><mixed-citation xml:lang="ru">Nimmi A. // Surgery. 2008. Vol. 144. P. 942-948.</mixed-citation><mixed-citation xml:lang="en">Nimmi A. // Surgery. 2008. Vol. 144. P. 942-948.</mixed-citation></citation-alternatives></ref><ref id="cit48"><label>48</label><citation-alternatives><mixed-citation xml:lang="ru">Kim Т. // BMC Cancer. 2008. Vol. 8. P. 296-307.</mixed-citation><mixed-citation xml:lang="en">Kim Т. // BMC Cancer. 2008. Vol. 8. P. 296-307.</mixed-citation></citation-alternatives></ref><ref id="cit49"><label>49</label><citation-alternatives><mixed-citation xml:lang="ru">Pelizzo M. // Eur. J. Surg. Oncol. 2006. Vol. 32. P. 1144-1448.</mixed-citation><mixed-citation xml:lang="en">Pelizzo M. // Eur. J. Surg. Oncol. 2006. Vol. 32. P. 1144-1448.</mixed-citation></citation-alternatives></ref><ref id="cit50"><label>50</label><citation-alternatives><mixed-citation xml:lang="ru">Ito Y. // World J. Surg. 2006. Vol. 30. P. 780-786.</mixed-citation><mixed-citation xml:lang="en">Ito Y. // World J. Surg. 2006. Vol. 30. P. 780-786.</mixed-citation></citation-alternatives></ref><ref id="cit51"><label>51</label><citation-alternatives><mixed-citation xml:lang="ru">Shin J. // Inter. J. of Surg. 2013. Vol. 11. P. 944-947.</mixed-citation><mixed-citation xml:lang="en">Shin J. // Inter. J. of Surg. 2013. Vol. 11. P. 944-947.</mixed-citation></citation-alternatives></ref><ref id="cit52"><label>52</label><citation-alternatives><mixed-citation xml:lang="ru">Repplingeri D. // J. Surg. Res. 2008. Vol. 150. P. 49-52.</mixed-citation><mixed-citation xml:lang="en">Repplingeri D. // J. Surg. Res. 2008. Vol. 150. P. 49-52.</mixed-citation></citation-alternatives></ref><ref id="cit53"><label>53</label><citation-alternatives><mixed-citation xml:lang="ru">Buyukasxik O. // Endokrynol. Pol. 2011. Vol. 62. P. 303-308.</mixed-citation><mixed-citation xml:lang="en">Buyukasxik O. // Endokrynol. Pol. 2011. Vol. 62. P. 303-308.</mixed-citation></citation-alternatives></ref><ref id="cit54"><label>54</label><citation-alternatives><mixed-citation xml:lang="ru">Fiore E. // Endocrinol. Relat. Cancer. 2011. Vol. 18. P. 429-437.</mixed-citation><mixed-citation xml:lang="en">Fiore E. // Endocrinol. Relat. Cancer. 2011. Vol. 18. P. 429-437.</mixed-citation></citation-alternatives></ref><ref id="cit55"><label>55</label><citation-alternatives><mixed-citation xml:lang="ru">Fiore E. // Endocrinol. Relat. Cancer. 2009. Vol. 16. P. 1251-1260.</mixed-citation><mixed-citation xml:lang="en">Fiore E. // Endocrinol. Relat. Cancer. 2009. Vol. 16. P. 1251-1260.</mixed-citation></citation-alternatives></ref><ref id="cit56"><label>56</label><citation-alternatives><mixed-citation xml:lang="ru">Haymart M. // Clin. Endocrinol. 2010. Vol. 71. P. 434-439.</mixed-citation><mixed-citation xml:lang="en">Haymart M. // Clin. Endocrinol. 2010. Vol. 71. P. 434-439.</mixed-citation></citation-alternatives></ref><ref id="cit57"><label>57</label><citation-alternatives><mixed-citation xml:lang="ru">Zafon C. // J. Thyroid Res. 2012. Vol. 5. P. 307-321.</mixed-citation><mixed-citation xml:lang="en">Zafon C. // J. Thyroid Res. 2012. Vol. 5. P. 307-321.</mixed-citation></citation-alternatives></ref><ref id="cit58"><label>58</label><citation-alternatives><mixed-citation xml:lang="ru">Cipolla C. // Am. Surg. 2005. Vol. 71. P. 874-878.</mixed-citation><mixed-citation xml:lang="en">Cipolla C. // Am. Surg. 2005. Vol. 71. P. 874-878.</mixed-citation></citation-alternatives></ref><ref id="cit59"><label>59</label><citation-alternatives><mixed-citation xml:lang="ru">Kebebew E. // World J. Surg. 2001. Vol. 25. P. 632-637.</mixed-citation><mixed-citation xml:lang="en">Kebebew E. // World J. Surg. 2001. Vol. 25. P. 632-637.</mixed-citation></citation-alternatives></ref><ref id="cit60"><label>60</label><citation-alternatives><mixed-citation xml:lang="ru">Larson S. // J. Am. Coll. Surg. 2007. Vol. 204. P. 764-775.</mixed-citation><mixed-citation xml:lang="en">Larson S. // J. Am. Coll. Surg. 2007. Vol. 204. P. 764-775.</mixed-citation></citation-alternatives></ref><ref id="cit61"><label>61</label><citation-alternatives><mixed-citation xml:lang="ru">Ahn D. // Acta Oncol. 2011. Vol. 50. P. 1228-1234.</mixed-citation><mixed-citation xml:lang="en">Ahn D. // Acta Oncol. 2011. Vol. 50. P. 1228-1234.</mixed-citation></citation-alternatives></ref><ref id="cit62"><label>62</label><citation-alternatives><mixed-citation xml:lang="ru">Huang B. // Endocrinol. Pathol. 2011. Vol. 22. P. 144-149.</mixed-citation><mixed-citation xml:lang="en">Huang B. // Endocrinol. Pathol. 2011. Vol. 22. P. 144-149.</mixed-citation></citation-alternatives></ref><ref id="cit63"><label>63</label><citation-alternatives><mixed-citation xml:lang="ru">Dvorkin S. // J. Clin. Endocrinol. Metab. 2013. Vol. 98, N 6. 2409-2414.</mixed-citation><mixed-citation xml:lang="en">Dvorkin S. // J. Clin. Endocrinol. Metab. 2013. Vol. 98, N 6. 2409-2414.</mixed-citation></citation-alternatives></ref><ref id="cit64"><label>64</label><citation-alternatives><mixed-citation xml:lang="ru">Luu Y. // Otolaryngology-Head and Neck Surg. 2012. Vol. 148, N 3. P. 396-402.</mixed-citation><mixed-citation xml:lang="en">Luu Y. // Otolaryngology-Head and Neck Surg. 2012. Vol. 148, N 3. P. 396-402.</mixed-citation></citation-alternatives></ref><ref id="cit65"><label>65</label><citation-alternatives><mixed-citation xml:lang="ru">Dean D. // Cancer Control. 2000. Vol. 7. P. 229-239.</mixed-citation><mixed-citation xml:lang="en">Dean D. // Cancer Control. 2000. Vol. 7. P. 229-239.</mixed-citation></citation-alternatives></ref><ref id="cit66"><label>66</label><citation-alternatives><mixed-citation xml:lang="ru">Jukkola A. // Endocrine-Resulted Cancer. 2004. Vol. 11. P. 551-579.</mixed-citation><mixed-citation xml:lang="en">Jukkola A. // Endocrine-Resulted Cancer. 2004. Vol. 11. P. 551-579.</mixed-citation></citation-alternatives></ref><ref id="cit67"><label>67</label><citation-alternatives><mixed-citation xml:lang="ru">Lang B. // Ann. Surg. 2007. Vol. 245. P. 366-378.</mixed-citation><mixed-citation xml:lang="en">Lang B. // Ann. Surg. 2007. Vol. 245. P. 366-378.</mixed-citation></citation-alternatives></ref><ref id="cit68"><label>68</label><citation-alternatives><mixed-citation xml:lang="ru">Lundgren C. // Cancer. 2006. Vol. 106. P. 524-531.</mixed-citation><mixed-citation xml:lang="en">Lundgren C. // Cancer. 2006. Vol. 106. P. 524-531.</mixed-citation></citation-alternatives></ref><ref id="cit69"><label>69</label><citation-alternatives><mixed-citation xml:lang="ru">Wada N. // J. Clin. Endocrinol. Metab. 2007. Vol. 92. P. 215-218.</mixed-citation><mixed-citation xml:lang="en">Wada N. // J. Clin. Endocrinol. Metab. 2007. Vol. 92. P. 215-218.</mixed-citation></citation-alternatives></ref><ref id="cit70"><label>70</label><citation-alternatives><mixed-citation xml:lang="ru">Yildirim E. // J. Am. Coll. Surg. 2005. Vol. 200. P. 378-392.</mixed-citation><mixed-citation xml:lang="en">Yildirim E. // J. Am. Coll. Surg. 2005. Vol. 200. P. 378-392.</mixed-citation></citation-alternatives></ref><ref id="cit71"><label>71</label><citation-alternatives><mixed-citation xml:lang="ru">Cooper D. // Thyroid. 2009. Vol. 19. P. 1167-1214.</mixed-citation><mixed-citation xml:lang="en">Cooper D. // Thyroid. 2009. Vol. 19. P. 1167-1214.</mixed-citation></citation-alternatives></ref><ref id="cit72"><label>72</label><citation-alternatives><mixed-citation xml:lang="ru">Pacini F. // Eur. J. Endocrinol. 2006. Vol. 154. P. 787-803.</mixed-citation><mixed-citation xml:lang="en">Pacini F. // Eur. J. Endocrinol. 2006. Vol. 154. P. 787-803.</mixed-citation></citation-alternatives></ref></ref-list><fn-group><fn fn-type="conflict"><p>The authors declare that there are no conflicts of interest present.</p></fn></fn-group></back></article>
