vestimИзвестия Национальной академии наук Беларуси. Серия медицинских наукProceedings of the National Academy of Sciences of Belarus, Medical series1814-60232524-2350The Republican Unitary Enterprise Publishing House "Belaruskaya Navuka"10.29235/1814-6023-2025-22-3-246-255vestim-1046Research ArticleКЛИНИЧЕСКАЯ И ЭКСПЕРИМЕНТАЛЬНАЯ МЕДИЦИНАCLINICAL AND EXPERIMENTAL MEDICINEПовышение эффективности профилактики воспалительных осложнений после дентальной имплантации при D-гиповитаминозе на основе прогностического моделированияImproving the efficiency of prevention of inflammatory complications after dental implantation in hypovitaminosis D based on prognostic modelinghttps://orcid.org/0000-0002-1686-1820БекжановаО. Е.BekjanovaO. E.

Бекжанова Ольга Есеновна – д-р мед. наук, профессор, заведующий кафедрой

ул. Сайрам, 25, 100170, г. Ташкент, Республика Узбекистан

Olga E. Bekjanova – D. Sc. (Med.), Professor, Headof the Department

25, Sayram Str., 100170, Tashkent, Republic of Uzbekistan

https://orcid.org/0000-0002-7450-3757РубниковичС. П.RubnikovichS. P.

Рубникович Сергей Петрович – д-р мед. наук, профессор, ректор.

пр. Дзержинского, 83, 220116, г. Минск, Республика Беларусь

Sergey P. Rubnikovich – D. Sc. (Med.), Professor, Rector

83, Dzerzhinski Ave., 220116, Minsk, Republic of Belarus

rubnikovichs@mail.ruhttps://orcid.org/0009-0002-1932-2985МаннановЖ. Ж.MannanovJ. J.

Маннанов Жавлонбек Жамолиддинович – канд. мед.наук, ст. преподаватель

ул. Сайрам, 25, 100170, г. Ташкент, Республика Узбекистан

Javlonbek J. Mannanov – Ph. D. (Med.), Senior Lecturer

25, Sayram Str., 100170, Tashkent, Republic of Uzbekistan

Ташкентский государственный стоматологический институтTashkent State Dental InstituteБелорусский государственный медицинский университетBelarusian State Medical University202531082025223246255Copyright © Бекжанова О.Е., Рубникович С.П., Маннанов Ж.Ж., 20252025Бекжанова О.Е., Рубникович С.П., Маннанов Ж.Ж.Bekjanova O.E., Rubnikovich S.P., Mannanov J.J.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://vestimed.belnauka.by/jour/article/view/1046

Несмотря на постоянное совершенствование методов нехирургической и хирургической терапии периимплантита, долгосрочный эффект проблематичен, поскольку даже при положительном эффекте терапии возможен рецидив. Предполагается, что одним из факторов, влияющих на развитие периимплантной патологии, является D-гиповитаминоз. Цель исследования – разработка модели прогнозирования риска развития воспалительных осложнений после дентальной имплантации у пациентов с D-гиповитаминозом. Разработанная модель включала такие показатели, как уровень витамина D в сыворотке крови, анатомо-топографическое положение и число имплантатов, возраст, наличие сахарного диабета II типа и соматической патологии воспалительного генеза. Установлен набор предикторов воспалительных осложнений дентальной имплантации, легко диагностируемый в рутинной практике, который может быть использован для осуществления лечебно-профилактических мероприятий. На основе многофакторной логистической регрессии разработана модель прогноза и ранней диагностики воспалительных осложнений после дентальной имплантации у пациентов с D-гиповитаминозом.

Despite the continuous improvement of methods for the non-surgical and surgical treatment of peri-implantitis, the long-term effect remains problematic. Even with positive effects of therapy, relapse is possible. Hypovitaminosis D is recognized as one of the factors in the development of peri-implant pathology. The objective of the research was to develop a risk profile for the development of inflammatory complications of dental implantation in patients with hypovitaminosis D based on prognostic modeling. A model for predicting inflammatory complications of dental implantation has been developed using logistic regression. The final model included vitamin D levels in blood serum, anatomical and topographic position, age, number of implants, the presence of type 2 diabetes mellitus, and somatic pathology of inflammatory origin. A set of predictors of inflammatory complications of dental implantation has been established, which is easily diagnosed in routine practice and can help in selecting patients for therapeutic and preventive measures. A model was developed for the prognosis and early diagnosis of inflammatory complications of dental implantation in patients with hypovitaminosis D. This model was developed using multifactorial logistic regression

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The authors declare that there are no conflicts of interest present.